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NCT07357701 · ClinicalTrials.gov registry record
Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)
A clinical trial of Primary Ovarian Insufficiency and Azoospermia, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
- Recruiting
- Registry status
- 500
- Enrollment target
- 2
- Study locations
NCT07357701 is a study of Primary Ovarian Insufficiency and Azoospermia that is actively recruiting participants, run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The registered enrollment target is 500 participants, above the 19-participant average among 3 other Primary Ovarian Insufficiency trials with a reported enrollment target (2532% higher). The trial reports 2 study locations across 1 state.
The verdict
NCT07357701, a study of Primary Ovarian Insufficiency and Azoospermia, is actively recruiting participants, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
- RECRUITING
- Registry status
- 500 participants
- Enrollment target
- 2
- Study locations
Study Summary
Background: Infertility affects 1 in 6 people. Often, the causes of infertility are unknown. Treatments are successful in only about 50% of cases. Infertility caused by non obstructive azoospermia in males and primary ovarian insufficiency in females can have genetic causes. Researchers want to learn more about these genes. Objective: To identify genes that may cause infertility. Eligibility: Adult men and women with non-obstructive azoospermia (NOA) or primary ovarian insufficiency (POI) of unknown cause. Design: Participants will provide a saliva sample. A kit will be sent to their home. The kit will contain a collection tube and a cotton swab. They will swirl the swab inside their mouth and then seal it in the tube. They will mail the tube back to the researchers. Male participants who are having a procedure done to collect tissue from their testes may opt to have leftover tissue provided to study researchers. This tissue would otherwise have been discarded. No new procedures will be performed just for this study. Data may be collected from participants medical records.
Conditions Studied
Study Locations (2)
Maryland
- National Institutes of Health Clinical Center (Remote and In-Person) - Bethesda
- Shady Grove Fertility - Rockville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2026-03-11 |
| Est. Completion | 2031-01-01 |
Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)305 total trials
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07357701
The ClinicalTrials.gov registry entry for NCT07357701 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 19-participant average among 3 other Primary Ovarian Insufficiency trials with a reported enrollment target (2532% higher). The listed sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Primary Ovarian Insufficiency appearing as the primary indexed condition, and to 0 interventions.
NCT07357701 reports 2 study locations spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT07357701 about?
NCT07357701 is a clinical study titled "Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)". Background: Infertility affects 1 in 6 people. Often, the causes of infertility are unknown. Treatments are successful in only about 50% of cases. Infertility caused by non obstructive azoospermia in males and primary ovarian insufficiency in females can have genetic causes. Researchers want to lea...
What is the current status of trial NCT07357701?
This trial is currently recruiting. The enrollment target is 500 participants. The study started on 2026-03-11. Estimated completion is 2031-01-01.
What conditions does trial NCT07357701 study?
This clinical trial studies the following conditions: Primary Ovarian Insufficiency, Azoospermia, Oligospermia.
Who is sponsoring clinical trial NCT07357701?
This trial is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07357701 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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