Eli Lilly and Company

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Eli Lilly and Company sits in the top decile of US sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count).

1,341 total trials 124 currently recruiting 1029 completed early-phase tilt top decile by trial count

Eli Lilly and Company: 1,341 sponsored US clinical trials, 124 recruiting.

Eli Lilly and Company sponsors 1,341 registered US clinical trials on ClinicalTrials.gov, 124 of them currently recruiting, and 1,029 completed. 459 of these trials are in Phase 3-4 (later-stage) and 861 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 55 trials.

Top-decile sponsor footprint

Eli Lilly and Company ranks in the top decile of sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 67/100

1,029 of 1,131 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,341 total, page 18 of 27

TERMINATED Phase 3

An Open Label Study for Participants With Rheumatoid Arthritis

NCT01215942

COMPLETED Phase 3

A Study in Prevention of Re-emergence of Depression Symptoms

NCT01299272

COMPLETED Phase 1

A Study of LY2495655 in Healthy Subjects

NCT01341470

COMPLETED Phase 2

A Study in Participants With End-Stage Renal Disease

NCT01200290

COMPLETED Phase 2

Study of Ramucirumab or Icrucumab (IMC-18F1) With Docetaxel or Docetaxel Alone as Second-Line Therapy in Participants With Bladder,Urethra, Ureter, or Renal Pelvis Carcinoma

NCT01282463

COMPLETED Phase 2

A Study of Ramucirumab in Participants With Gastric, Esophageal, and Gastroesophageal Cancer

NCT01246960

COMPLETED Phase 2

A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck

NCT01059643

COMPLETED Phase 1

A Study Combining LY2157299 With Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma

NCT01220271

COMPLETED Phase 2

A Study in Non-Small Cell Lung Cancer

NCT01232452

COMPLETED Phase 2

A Study of LY2157299 in Participants With Hepatocellular Carcinoma

NCT01246986

COMPLETED Phase 1

A Study of Anti-VEGFR-3 Monoclonal Antibody IMC-3C5 in Subjects With Advanced Solid Tumors

NCT01288989

COMPLETED Phase 3

A Study of Duloxetine in Adolescents With Juvenile Primary Fibromyalgia Syndrome

NCT01237587

COMPLETED Phase 3

A Study in Participants With Major Depressive Disorder Who Are Partial Responders to Selective Serotonin Reuptake Inhibitor

NCT01185340

COMPLETED Phase 2

Study of Icrucumab (IMC-18F1) or Ramucirumab Drug Product (DP) in Combination With Capecitabine or Capecitabine on Previously Treated Breast Cancer Patients

NCT01234402

COMPLETED Phase 3

A Study of Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Disorder Who Have Had a Partial Response to Selective Serotonin Reuptake Inhibitor (SSRI) Treatment

NCT01187407

COMPLETED Phase 1

A Study of the Effect of LY2189265 on Two Blood Pressure Drugs

NCT01324388

TERMINATED Phase 3

Hospital Management of Hyperglycemia Study of Insulin Glargine Plus Insulin Lispro Versus Human Regular Insulin

NCT01136746

COMPLETED Phase 1

A Study to Compare the Concentrations of LY2189265 After Different Methods of Administration to Healthy Volunteers.

NCT01301092

COMPLETED Phase 1

Disposition of 14C-LY3009104 Following Oral Administration in Healthy Human Subjects

NCT01299285

COMPLETED Phase 2

A Study of LY2409021 in Patients With Type 2 Diabetes

NCT01241448

COMPLETED Phase 1

Disposition of 14C-LY2452473 Following Oral Administration in Healthy Human Subjects

NCT01275157

COMPLETED Phase 3

A Rheumatoid Arthritis Study in Participants

NCT01202760

COMPLETED Phase 3

A Study of LY2127399 in Participants With Systemic Lupus Erythematosus

NCT01205438

TERMINATED Phase 2

A Study in Migraine Prevention

NCT01184508

TERMINATED Phase 3

A Study in Participants With Rheumatoid Arthritis

NCT01202773

COMPLETED Phase 3

A Study in Second Line Metastatic Colorectal Cancer

NCT01183780

COMPLETED Phase 1

A Study of LY2216684 and Digoxin in Healthy Subjects

NCT01266590

COMPLETED Phase 1

A Safety Study of LY2886721 Multiple Doses in Healthy Subjects

NCT01227252

COMPLETED Phase 1

A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol

NCT01263197

COMPLETED Phase 3

A Study of Paclitaxel With or Without Ramucirumab (IMC-1211B) in Metastatic Gastric Adenocarcinoma

NCT01170663

COMPLETED Phase 4

Study of Insulin Lispro in Participants With Inadequately Controlled Type 2 Diabetes

NCT01215955

COMPLETED Phase 1

A Study of Brain Receptor Occupancy in Healthy Subjects

NCT01232439

COMPLETED Phase 3

A Study of Chemotherapy and Ramucirumab Versus Chemotherapy Alone in Second Line Non-Small Cell Lung Cancer (NSCLC) Participants Who Received Prior First Line Platinum-based Chemotherapy

NCT01168973

COMPLETED Phase 1

A Pharmacokinetic Study on the Effect of LY2216684 on the Active Metabolite of Clopidogrel

NCT01263093

COMPLETED Phase 3

A Study of LY2127399 in Participants With Systemic Lupus Erythematosus

NCT01196091

COMPLETED Phase 1

A Study of LY2216684 in Major Depressive Disorder in Patients Taking Selective Serotonin Reuptake Inhibitors

NCT01263223

COMPLETED Phase 1

A Study of LY2216684 and Warfarin in Healthy Subjects

NCT01263119

COMPLETED Phase 1

A Study of LY2216684 and Theophylline in Healthy Subjects

NCT01263106

TERMINATED Phase 3

Continued Safety Monitoring of Solanezumab (LY2062430) in Alzheimer's Disease

NCT01127633

TERMINATED Phase 3

A Rheumatoid Arthritis Study in Participants on a Background Treatment of Methotrexate

NCT01198002

COMPLETED Phase 1

A Pharmacokinetic Study of the Coadministration of LY2216684 With Sertraline

NCT01250873

COMPLETED Phase 1

A Study of LY3009104(Baricitinib) for Healthy Subjects

NCT01247350

COMPLETED Phase 3

A Fixed Dose Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder

NCT01173601

COMPLETED Phase 3

A Study in Participants With Type 2 Diabetes Mellitus (AWARD-4)

NCT01191268

COMPLETED Phase 1

A Multiple-Dose Study to Evaluate Skin Irritation and Sensitization of Teriparatide Administered Transdermally in Healthy Postmenopausal Women

NCT01250145

COMPLETED Phase 2

A Study in Participants With Acute Leukemia

NCT01214603

COMPLETED Phase 1

A Study of LY2608204 in Patients With Type 2 Diabetes

NCT01247363

COMPLETED Phase 1

A Study of LY2216684 in Participants With Impaired Hepatic Function

NCT01241435

COMPLETED Phase 3

A Study of Ramucirumab (IMC-1121B) Drug Product (DP) and Best Supportive Care (BSC) Versus Placebo and BSC as 2nd-Line Treatment in Participants With Hepatocellular Carcinoma After 1st-Line Therapy With Sorafenib

NCT01140347

COMPLETED Phase 3

A Safety Study in Participants With Major Depressive Disorder

NCT01155661

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Phase Distribution

PhaseTrial count
Phase 1 517
Phase 2 344
Phase 3 368
Phase 4 91

What is open in the Eli Lilly and Company pipeline

124 recruiting of 1,341 indexed (9% open); 1,029 completed (77%).

Phase mix: 459 late (III/IV) vs 861 early (I/II) (early-phase heavy).

Top condition: Healthy (55 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Eli Lilly and Company: open-pipeline peers nationwide

Peers matched on 1,341 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15% Total trials Recruiting share Eli Lilly and CompanyGlaxoSmithKlineUniversity of MichiganNovartis PharmaceuticalsAstraZenecaShionogiUniversity of KentuckyUniversity of VermontLahey Clinic
Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,341 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this Eli Lilly and Company page

1,341 registered trials is a research-attention snapshot, not an endorsement of Eli Lilly and Company or any single study.

  • 124 of Eli Lilly and Company's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition Eli Lilly and Company studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Eli Lilly and Company pipeline card: 1,341 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.