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NCT05465382 · ClinicalTrials.gov registry record · NA
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures
A NA study, sponsored by Duke University.
- Terminated
- Registry status
- NA
- Development phase
- 41
- Enrollment target
NCT05465382 is a NA study that was terminated before completion, run by Duke University. The registered enrollment target is 41 participants.
The verdict
NCT05465382, a NA study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- NA
- Development phase
- 41 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human ankle. We hypothesize that early intervention with percutaneous joint lavage in the first 0-48 hours after injury will attenuate the production of pro-inflammatory cytokines, MMP's and cartilage breakdown products compared to non-lavaged control subjects at the time of surgical fixation.
Interventions
- DEVICE Saline Lavage
- OTHER No intra-articular saline lavage
- DRUG Lidocaine - intra-articular injection
- OTHER Synovial Fluid Aspiration
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2022-07-22 |
| Est. Completion | 2024-05-07 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05465382
The ClinicalTrials.gov registry entry for NCT05465382 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Saline Lavage is the first listed.
NCT05465382 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05465382 about?
NCT05465382 is a clinical study titled "Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures". The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human ankle. We hypothesize that early intervention with percutaneous joint lavag...
What is the current status of trial NCT05465382?
This trial is currently terminated. It is a NA study. The enrollment target is 41 participants. The study started on 2022-07-22. Estimated completion is 2024-05-07.
What interventions are being tested in trial NCT05465382?
The interventions under investigation include: Saline Lavage (DEVICE), No intra-articular saline lavage (OTHER), Lidocaine - intra-articular injection (DRUG), Synovial Fluid Aspiration (OTHER).
Who is sponsoring clinical trial NCT05465382?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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