Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 31 of 35

TERMINATED Phase 2

Adjuvant Cisplatin With Either Genomic-Guided Vinorelbine or Pemetrexed for Early Stage Non-Small-Cell Lung Cancer

NCT00545948

TERMINATED NA

Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis

NCT00567437

COMPLETED Phase 2

Cephalon Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndrome

NCT00621023

TERMINATED Phase 2

Phase II Study Evaluating The Safety And Response To Neoadjuvant Dasatinib In Early Stage Non-Small Cell Lung Cancer

NCT00564876

COMPLETED Phase 1

Sorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or Leg

NCT00565968

COMPLETED NA

Feasibility of Cocooning Immunization Strategy With Influenza Vaccine

NCT00570037

COMPLETED NA

Partnership for Glaucoma

NCT00672048

COMPLETED Phase 2

Phase II Dasatinib Study in Advanced Breast Cancer

NCT00546104

COMPLETED NA

Guided Imagery for Military Sexual Trauma-Related Posttraumatic Stress Disorder (PTSD)

NCT00635635

COMPLETED NA

KAN-DO: A Family-based Intervention to Prevent Childhood Obesity

NCT00563264

COMPLETED Phase 2

Ph. 2 Sorafenib + Protracted Temozolomide in Recurrent GBM

NCT00597493

COMPLETED

Automated Chest Physiotherapy to Improve Outcomes in Neuro

NCT00571623

COMPLETED Phase 1

Behavioral Insomnia Therapy With Chronic Fatigue Syndrome

NCT00540254

COMPLETED Phase 4

How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis

NCT00528788

COMPLETED Phase 4

Aprepitant With Dexamethasone Versus Ondansetron With Dexamethasone for PONV Prophylaxis in Patients Having Craniotomy

NCT00734929

COMPLETED Phase 2

Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas

NCT00612339

COMPLETED

Duke Autoimmunity in Pregnancy Registry

NCT00513591

COMPLETED Phase 3

Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis

NCT00517933

COMPLETED Phase 3

Concurrent Nicotine Patch / Denicotinized Cigarette Therapy for Smoking Cessation II

NCT00734617

COMPLETED

Erythropoietin Resistance in Anemia of Chronic Kidney Disease

NCT00526747

COMPLETED NA

A Trial of Aprepitant For Prevention of Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis

NCT00736073

TERMINATED Phase 2

Polycystic Ovarian Syndrome: Impact of Flaxseed Supplementation

NCT00693082

COMPLETED Phase 2

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

NCT00597402

COMPLETED Phase 2

Ketamine In Thoracic Surgery (KITS) Trial

NCT00504725

COMPLETED

Risk of Life-threatening Heart Rhythm Disturbances in Siblings

NCT00498524

COMPLETED Phase 2

Engaging Motivation for the Prevention of Weight Regain

NCT01169428

COMPLETED Phase 2

Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma

NCT00501891

TERMINATED

Insulin Resistance in Nonalcoholic Fatty Liver Disease: A Case Control Study

NCT00637520

COMPLETED

Total Ankle Replacement for Ankle Arthritis

NCT01986244

COMPLETED Phase 1

Study of Cancer Peptides Vaccine Plus GM-CSF as Adjuvant Treatment for High Risk (TXN2-3M0) or Metastatic Breast Cancer With No Evidence of Disease

NCT00674791

TERMINATED NA

Computerized Cognitive Training for Childhood Cancer Survivors

NCT00629395

COMPLETED NA

CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00427193

COMPLETED NA

Coping in African American Prostate Cancer Survivors

NCT00589966

COMPLETED

Antidepressant Safety in Kids Study

NCT00395213

COMPLETED Phase 2

Phase II Study With Abraxane, Bevacizumab and Carboplatin in Triple Negative Metastatic Breast Cancer

NCT00479674

COMPLETED

Pharmacogenomics of Antidepressant Response in Children and Adolescents

NCT00516932

COMPLETED Phase 4

The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty

NCT00620828

TERMINATED Phase 2

Study Using a Genomic Predictor of Platinum Resistance to Guide Therapy in Stage IIIB/IV Non-Small Cell Lung Cancer

NCT00509366

TERMINATED Phase 2

A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain

NCT00476827

COMPLETED Early Phase 1

Early Detection of Lung Cancer Via Bi-plane Correlation Chest Imaging

NCT00673283

COMPLETED Phase 2

Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme

NCT00672243

COMPLETED Phase 2

Pilot Study of Duloxetine in Psychological Resilience

NCT00331799

TERMINATED Phase 1

A Phase I/Expansion Study of Dasatinib

NCT00598091

TERMINATED NA

Alcohol in the Treatment of Obesity

NCT00594074

COMPLETED Phase 4

The Treatment of Insomnia in Patients With HIV Disease

NCT00465972

COMPLETED Phase 2

Ph II Bevacizumab + Etoposide for Pts w Recurrent MG

NCT00612430

COMPLETED Phase 1

Metabolic Signatures and Biomarkers in Schizophrenia

NCT00466310

COMPLETED Phase 2

Oxaliplatin, Capecitabine and Avastin for Metastatic Esophagogastric Adenocarcinoma

NCT00447330

COMPLETED Phase 2

Phase (Ph) II Bevacizumab + Erlotinib for Patients (Pts) With Recurrent Malignant Glioma (MG)

NCT00671970

COMPLETED Phase 3

Study of Bimatoprost Gel on Eyelash Growth

NCT01200251

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.