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NCT00517933 · ClinicalTrials.gov registry record · Phase 3
Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis
A Phase 3 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 3
- Development phase
- 180
- Enrollment target
NCT00517933: Completed Phase 3 study, sponsored by Duke University.
NCT00517933 is a Phase 3 study that has completed, run by Duke University. The registered enrollment target is 180 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00517933, a Phase 3 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 180 participants
- Enrollment target
Study Summary
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects an individual's ability to breathe. This study will evaluate the effectiveness of sildenafil, a medication that increases blood flow to the lungs, at improving breathing function, exercise capacity, and quality of life in people with advanced IPF.
Primary Outcome
This is a binary score (1 or 0) with 1 being better than 0. All models adjust for baseline values of age, height, sex, white race, and DLCO. Values from models are estimated changes from baseline to 12 weeks (with 95% confidence intervals). The difference estimate is based on sildenafil - placebo.
Interventions
- OTHER Placebo
- DRUG Sildenafil Citrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2007-08 |
| Est. Completion | 2009-10 |
| Phase | Phase 3 |
What the finished NCT00517933 record still lists
NCT00517933 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00517933 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00517933 about?
NCT00517933 is a clinical study titled "Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis". Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects an individual's ability to breathe. This study will evaluate the effectiveness of sildenafil, a medication that increases blood flow to the lungs, at improving breathing function, exercise capacity, and quality of life in peo...
What is the current status of trial NCT00517933?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 180 participants. The study started on 2007-08. Estimated completion is 2009-10.
What interventions are being tested in trial NCT00517933?
The interventions under investigation include: Placebo (OTHER), Sildenafil Citrate (DRUG).
Who is sponsoring clinical trial NCT00517933?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00517933's enrollment target sits among peer trials
180 1422nd of 2000 higher than 564 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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