Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00546104 · ClinicalTrials.gov registry record · Phase 2

Phase II Dasatinib Study in Advanced Breast Cancer

A Phase 2 study, sponsored by Duke University.

Completed
Registry status
Phase 2
Development phase
31
Enrollment target

NCT00546104: Completed Phase 2 study, sponsored by Duke University.

NCT00546104 is a Phase 2 study that has completed, run by Duke University. The registered enrollment target is 31 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00546104, a Phase 2 study, has completed, sponsored by Duke University.

COMPLETED
Registry status
Phase 2
Development phase
31 participants
Enrollment target

Study Summary

The purpose of this study is to find out if dasatinib will safely reduce the size or spread of your tumor.

Primary Outcome

Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0), as a 20% increase in the sum of the longest diameter of target lesions, or measurable increase in a non-target lesion, or the appearance of new lesions, or similar definition as appropriate. Proportion progression-free at 16 weeks.From first day of study related treatment with Dasatinib until the date of first documented progression or date of death from any cause, whichever came first.

Interventions

  • DRUG Dasatinib

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2007-10
Est. Completion 2011-05
Phase Phase 2
Duke University

1,725 total trials

What the finished NCT00546104 record still lists

NCT00546104 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 1 intervention - of which Dasatinib is the first listed.

NCT00546104 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00546104 about?

NCT00546104 is a clinical study titled "Phase II Dasatinib Study in Advanced Breast Cancer". The purpose of this study is to find out if dasatinib will safely reduce the size or spread of your tumor.

What is the current status of trial NCT00546104?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 31 participants. The study started on 2007-10. Estimated completion is 2011-05.

What interventions are being tested in trial NCT00546104?

The interventions under investigation include: Dasatinib (DRUG).

Who is sponsoring clinical trial NCT00546104?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00546104's enrollment target sits among peer trials

31 1578th of 2000 higher than 419 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02932618 · 31 participants · Phase 3

    A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)

  • NCT03482297 · 31 participants · Phase 1

    Automated Abdominal Binder for Orthostatic Hypotension

  • NCT04016389 · 31 participants · NA

    FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery

  • NCT04211675 · 31 participants · Phase 1

    NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00546104, the US trial registry maintained by the National Library of Medicine. NCT00546104 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.