Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 11 of 35
Improving Veteran Access to Integrated Management of Back Pain
NCT04411420
Open Label Phase I hCT-MSC in Toddlers With Autism Spectrum Disorder
NCT04294290
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Chronic Pain Trial)
NCT05966142
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center)
NCT04445792
A Needs-focused Palliative Care Intervention for Older Adults in ICUs
NCT04414787
Enhancing the Transition From Hospital to Home for Patients With Traumatic Brain Injury and Families
NCT04584554
Advance Care Planning Notifications in General Inpatient Medicine
NCT04756583
Meaning-Centered Pain Coping Skills Training
NCT04431830
In-Field Detection of Intracranial Pressure
NCT04515212
The Benchmark Clinic: An Interdisciplinary Comprehensive Care Model for People With Parkinson Disease
NCT04555720
Learn to Quit-HIV Pilot Study
NCT04609514
Lift Mobile Mindfulness for COVID-19 Distress Symptoms
NCT04581200
Surgeon Infiltration QL Block Comparison
NCT03496610
PTSD Mobile App for Cancer Survivors
NCT04058795
Tasso-SST OnDemand Comparator Pilot Study
NCT04713748
Physical Activity to Improve Patient Reported Outcomes for Adults With Acute Leukemia
NCT04552912
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer
NCT04563130
PROSPective Evaluation of Fortified Eggs Related to Improvement in The Biomarker Profile for Your Health
NCT04673721
Reliability and Reproducibility of the Eye Check Tonometer
NCT04639947
Increasing Physical Activity in Older Adults With Osteoarthritis Pain: Examining a Brief Behavioral Intervention
NCT04490395
CAMPUS - Feasibility Sub-Study
NCT04728815
Brief mHealth Self-Compassion Intervention on Internalized Weight Bias
NCT04678973
Hyperbaric Oxygen and Outcome After Below Knee Amputations
NCT04717557
Quantitative MRI for Functional Assessment Following SBRT for Spinal Metastases
NCT04248543
Exploring the Acceptability and Efficacy of a Transdiagnostic Treatment for Misophonia
NCT04612374
Multiple Myeloma/Chronic Lymphocytic Leukemia Coach RCT
NCT05928156
The Baerveldt Versus ClearPath Comparison Study
NCT04468633
A+ Treatment/Feasibility of Adapted ESDM-informed Caregiver Coaching Delivered Remotely for Children With ASD (Autism Spectrum Disorder) and ADHD (Attention Deficit Hyperactivity Disorder)
NCT05417607
Development and Testing of ADEPT: A Parent Decision Support for Childhood Vaccinations
NCT04496453
Network-Targeted Strategies for Efficient Community SARS-CoV-2 (COVID-19) Sampling
NCT04437706
Evaluation of Pain and Discomfort in the Cardiac Catheterization Lab
NCT04490369
Mobile Coping Skills Training to Improve Cardiorespiratory Failure Survivors' Psychological Distress
NCT04329702
a/LCI-OCT Pilot in Esophagus
NCT04392167
Duke Transplant University
NCT04219839
Targeting the Health Care Provider (HCP) Burnout Crisis During the COVID-19 Pandemic
NCT04632368
Glucagon Receptor Inhibition to Enable Breast Cancer Patients to Benefit From PI3K Inhibitor Therapy (REMD-477)
NCT04330625
Multi-Drug Resistant Organism (MDRO): Study of Highly Resistant Escherichia Coli
NCT04574596
Providing Suboxone and PrEP Using Telemedicine
NCT04521920
Identifying the Optimal Neural Target for Misophonia Interventions
NCT04348591
4DX Functional Lung Imaging in the Diagnosis of Chronic Lung Allograft Dysfunction After Lung Transplantation
NCT04892719
Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease
NCT04584528
Intergenerational Effects of Paternal Periconceptional Cannabis and Other Drug Use (EPIC)
NCT04436055
Coping Together: Couple-based Interventions for Cancer
NCT04590885
A Text-based Reduction Intervention for Smokeless Tobacco Cessation
NCT04315506
The Integration of a Mobile App Platform With Biomarkers in Kidney Transplantation
NCT04382248
ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients
NCT04423939
Dry Needling for Shoulder Adhesive Capsulitis
NCT03861923
Case Managers for CVD Risk Reduction in HIV Clinic
NCT03839394
The Effects of Western Diet Patterns on Plasma Inflammatory and Cardio Metabolic Health Signatures in Middle-aged Adults
NCT04275843
Nourish: A Digital Health Program to Promote the DASH Eating Plan Among Adults With High Blood Pressure
NCT03875768
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.