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NCT04730557 · ClinicalTrials.gov registry record · NA
Reducing Obesity and Cartilage Compression in Knees
A NA study, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 88
- Enrollment target
NCT04730557 is a NA study that has completed, run by Duke University. The registered enrollment target is 88 participants.
The verdict
NCT04730557, a NA study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 88 participants
- Enrollment target
Study Summary
OA is a degenerative joint disease that involves the degradation of articular cartilage and underlying subchondral bone. Obesity is identified as a critical and potentially modifiable risk factor for the development and progression of OA. The first objective of the study is to determine the effects of obesity on cartilage composition and function. The second objective of the study is to determine whether weight loss restores cartilage composition and function. Study activities would require getting MR Imaging, evaluation of joint loading using gait analysis techniques, cartilage strain measurement, and participating in weight loss intervention. The study will target a population age group between 18 and 45 years with a BMI greater than or equal to 29. Data analyses will be blinded to reduce potential bias. All subjects participating in this study will be informed of the risks involved and sign an IRB-approved consent form.
Interventions
- BEHAVIORAL Weight Loss
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2020-06-05 |
| Est. Completion | 2024-05-17 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04730557
The ClinicalTrials.gov registry entry for NCT04730557 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Weight Loss is the first listed.
NCT04730557 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04730557 about?
NCT04730557 is a clinical study titled "Reducing Obesity and Cartilage Compression in Knees". OA is a degenerative joint disease that involves the degradation of articular cartilage and underlying subchondral bone. Obesity is identified as a critical and potentially modifiable risk factor for the development and progression of OA. The first objective of the study is to determine the effects ...
What is the current status of trial NCT04730557?
This trial is currently completed. It is a NA study. The enrollment target is 88 participants. The study started on 2020-06-05. Estimated completion is 2024-05-17.
What interventions are being tested in trial NCT04730557?
The interventions under investigation include: Weight Loss (BEHAVIORAL).
Who is sponsoring clinical trial NCT04730557?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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