Daiichi Sankyo

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Daiichi Sankyo sits in the top decile of US sponsors by registered trial count (#139 of 15,742 sponsors by registered trial count).

236 total trials 29 currently recruiting 167 completed early-phase tilt top decile by trial count

Daiichi Sankyo: 236 sponsored US clinical trials, 29 recruiting.

Daiichi Sankyo sponsors 236 registered US clinical trials on ClinicalTrials.gov, 29 of them currently recruiting, and 167 completed. 71 of these trials are in Phase 3-4 (later-stage) and 153 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Advanced Solid Tumor, with 7 trials.

Top-decile sponsor footprint

Daiichi Sankyo ranks in the top decile of sponsors by registered trial count (#139 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

167 of 189 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

236 total, page 2 of 5

COMPLETED Phase 1

A Study to Evaluate QTc Prolongation With Quizartinib in Healthy Subjects Under Rapid Acceleration of Heart Rate

NCT06772246

COMPLETED

A Study Assessing Risk Factors for Oral Mucositis/Stomatitis and Ocular Surface Events in NSCLC and Breast Cancer

NCT06686602

COMPLETED

Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment

NCT06557967

COMPLETED

Study of Predictors of Clinical Outcomes in Patients With HR+ and HER2-low/Negative Breast Cancer

NCT06040593

COMPLETED Phase 1

A Study of DS-7011a in Patients With Systemic Lupus Erythematosus

NCT05638802

COMPLETED

A Study of Prevalence of HER3 Expression in Non-Small Cell Lung Cancer

NCT05769764

COMPLETED Phase 1

A Study to Assess the Safety and Pharmacokinetics of Multiple Ascending Subcutaneous Doses of DS-2325a in Healthy Subjects

NCT05583669

COMPLETED Phase 2

A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum

NCT05569252

COMPLETED Phase 1

A Study to Assess the Safety and Pharmacokinetics of Single Ascending Subcutaneous and Intravenous Doses of DS-2325a in Healthy Subjects

NCT05388903

TERMINATED Phase 1

A Study of DS-9606a in Patients With Advanced Solid Tumors

NCT05394675

COMPLETED Phase 1

A Study of a Single Ascending Dose Study of DS-7011a in Healthy Subjects

NCT05203692

COMPLETED

Pseudoxanthoma Elasticum (PXE) Natural History Biomarkers in PXE Individuals and Their Biological Non-PXE Siblings

NCT05025722

COMPLETED Phase 2

Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)

NCT04484142

COMPLETED Phase 2

Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)

NCT04644237

COMPLETED Phase 2

Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer

NCT04744831

COMPLETED Phase 4

Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) Previously Treated With Pexidartinib

NCT04526704

COMPLETED Phase 1

A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment

NCT04473664

TERMINATED Phase 2

A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer

NCT04479436

TERMINATED Phase 1

DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST)

NCT04276415

COMPLETED Early Phase 1

Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

NCT04223635

COMPLETED Phase 2

DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)

NCT04014075

COMPLETED Phase 1

Study of Single-dose DS-3201b in Participants With Hepatic Impairment

NCT04276662

COMPLETED Phase 1

Effect of Low-Fat Food on Pexidartinib Pharmacokinetics in Healthy Volunteers

NCT03901313

TERMINATED Phase 1

Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)

NCT03552029

COMPLETED Early Phase 1

Food Effects on Milademetan Pharmacokinetics in Healthy Participants

NCT03647202

COMPLETED Phase 1

Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer

NCT03523572

COMPLETED Phase 3

DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]

NCT03523585

COMPLETED Early Phase 1

Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy Participants

NCT03614455

TERMINATED Phase 2

DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing or -Mutated Non-Small Cell Lung Cancer

NCT03505710

COMPLETED Phase 3

Edoxaban for Prevention of Blood Vessels Being Blocked by Clots (Thrombotic Events) in Children at Risk Because of Cardiac Disease

NCT03395639

COMPLETED Phase 1

Effect of Pexidartinib on the Way the Body Processes CYP3A4 and CYP2C9 Substrates (Pharmacokinetics)

NCT03291288

COMPLETED

Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)

NCT04033094

TERMINATED Phase 2

A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1)

NCT03248492

COMPLETED Phase 1

DS2330b Alone and With Sevelamer in Patients on Chronic Hemodialysis

NCT03305471

TERMINATED Phase 1

DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL)

NCT03110354

COMPLETED Phase 3

Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

NCT02798471

COMPLETED Phase 3

Edoxaban Compared to Standard Care After Heart Valve Replacement Using a Catheter in Patients With Atrial Fibrillation (ENVISAGE-TAVI AF)

NCT02943785

COMPLETED Phase 1

Effect of Probenecid on Pexidartinib Pharmacokinetics

NCT03138759

TERMINATED Phase 1

Antibody DS-8273a Administered in Combination With Nivolumab in Subjects With Advanced Colorectal Cancer

NCT02991196

COMPLETED

Tenosynovial Giant Cell Tumors (TGCT) Observational Platform Project

NCT02948088

COMPLETED Phase 3

Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML)

NCT02668653

COMPLETED Phase 1

Study to Assess the Safety, Pharmacokinetics/Dynamics of DS-1040b in Subjects With Acute Submassive Pulmonary Embolism

NCT02923115

COMPLETED Phase 1

A Study to Determine the Effects of Itraconazole on the Pharmacokinetics (PK) of DS-8500 in Healthy Subjects

NCT02790671

COMPLETED Phase 1

A Study Assessing the Mass Balance of a Single Oral Dose of [14C] DS-8500a in Healthy Subjects

NCT02790684

COMPLETED Phase 2

12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin

NCT02647320

COMPLETED Phase 1

The Effect of CS-3150 Exposure on Corrected QT (QTc) Interval Duration in Healthy Volunteers

NCT04019652

COMPLETED Phase 1

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke

NCT02586233

COMPLETED Phase 3

Cancer Venous Thromboembolism (VTE)

NCT02073682

TERMINATED Phase 1

A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors

NCT02452424

COMPLETED Phase 1

Study of DS-7080a for the Treatment of Macular Degeneration

NCT02530918

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 63
Phase 3 50
Phase 4 21

What is open in the Daiichi Sankyo pipeline

29 recruiting of 236 indexed (12% open); 167 completed (71%).

Phase mix: 71 late (III/IV) vs 153 early (I/II) (early-phase heavy).

Top condition: Advanced Solid Tumor (7 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Daiichi Sankyo: open-pipeline peers nationwide

Peers matched on 236 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

Daiichi Sankyo sits below the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500600 10%12%14%16%18%20% Total trials Recruiting share Daiichi SankyoLoma Linda UniversityHenry Ford Health SystemIncyte CorporationUniversity of Massachusetts, WorcesterUniversity of IowaAugusta UniversityNational Institute of Mental Health (NIMH)National Heart, Lung, and Blood Institute (NHLBI)
Daiichi Sankyo sits below the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Daiichi Sankyo sits below the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 236 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this Daiichi Sankyo page

236 registered trials is a research-attention snapshot, not an endorsement of Daiichi Sankyo or any single study.

  • 29 of Daiichi Sankyo's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Advanced Solid Tumor is the condition Daiichi Sankyo studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Advanced Solid Tumor trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Daiichi Sankyo pipeline card: 236 registered trials from official public datasets.Report a data error.