City of Hope Medical Center

582 total trials 167 currently recruiting 217 completed

City of Hope Medical Center sponsors 582 registered US clinical trials on ClinicalTrials.gov, 167 of them currently recruiting, and 217 completed. 9 of these trials are in Phase 3-4 (later-stage) and 382 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Acute Myeloid Leukemia, with 22 trials.

Trial Pipeline

582 total, page 5 of 12

ACTIVE NOT RECRUITING Phase 1

CF33-hNIS-antiPDL1 for the Treatment of Metastatic Triple Negative Breast Cancer

NCT05081492

ACTIVE NOT RECRUITING NA

App-Based Mindfulness Intervention for the Improvement of Quality of Life in Patients With Metastatic Renal Cell Cancer

NCT04788095

ACTIVE NOT RECRUITING Phase 1

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

NCT04605731

ACTIVE NOT RECRUITING NA

A Multidisciplinary Approach to Improve the Health of Older Adults With Blood Cancers After Stem Cell Transplantation

NCT04914338

ACTIVE NOT RECRUITING Phase 1

LB-100, Carboplatin, Etoposide, and Atezolizumab for the Treatment of Untreated Extensive-Stage Small Cell Lung Cancer

NCT04560972

ACTIVE NOT RECRUITING Phase 2

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

NCT04519879

ACTIVE NOT RECRUITING Phase 2

Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

NCT04783415

ACTIVE NOT RECRUITING Phase 2

Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic Leukemia

NCT04657094

ACTIVE NOT RECRUITING NA

A Nurse-Led Intervention for Fear of Progression in Advanced Cancer

NCT04819997

ACTIVE NOT RECRUITING Phase 1

Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma

NCT04661384

ACTIVE NOT RECRUITING NA

Home Base Telemonitoring in Gastrointestinal, Genitourinary, or Gynecologic Cancer Patients Undergoing Abdominal Surgery

NCT04596384

ACTIVE NOT RECRUITING Phase 2

Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

NCT04665765

ACTIVE NOT RECRUITING

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

NCT04537871

ACTIVE NOT RECRUITING Phase 2

Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation

NCT04339101

ACTIVE NOT RECRUITING NA

Technology-Enabled Activation of Skin Cancer Screening for Stem Cell Transplant Survivors and Their Primary Care Providers, TEACH Study

NCT04358276

ACTIVE NOT RECRUITING Early Phase 1

Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma

NCT04370483

ACTIVE NOT RECRUITING

Analysis of Coronavirus Disease 19 (COVID-19) Convalescent Plasma

NCT04497779

ACTIVE NOT RECRUITING Phase 3

Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

NCT04428905

ACTIVE NOT RECRUITING Phase 2

Intermittent Duvelisib Dosing in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT03961672

ACTIVE NOT RECRUITING Phase 1

Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease

NCT04212416

ACTIVE NOT RECRUITING Phase 1

Brigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLC

NCT04227028

ACTIVE NOT RECRUITING Phase 1

TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT

NCT04281199

ACTIVE NOT RECRUITING Phase 1

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

NCT04214392

ACTIVE NOT RECRUITING Phase 2

Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

NCT04262843

ACTIVE NOT RECRUITING NA

Telehealth for the Self-Management of Dietary Quality of Life in Patients After Stomach Cancer Surgery

NCT05203627

ACTIVE NOT RECRUITING Phase 2

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

NCT04200443

ACTIVE NOT RECRUITING Phase 2

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

NCT04060277

ACTIVE NOT RECRUITING Phase 1

PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer

NCT03873805

ACTIVE NOT RECRUITING Phase 1

Pembrolizumab and Blinatumomab in Treating Participants With Recurrent or Refractory Acute Lymphoblastic Leukemia

NCT03512405

ACTIVE NOT RECRUITING Phase 2

Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma

NCT03346135

ACTIVE NOT RECRUITING Phase 1

CBM588 in Improving Clinical Outcomes in Patients Who Have Undergone Donor Hematopoietic Stem Cell Transplant

NCT03922035

ACTIVE NOT RECRUITING NA

Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease

NCT03865992

ACTIVE NOT RECRUITING Phase 1

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

NCT03884998

ACTIVE NOT RECRUITING Phase 1

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

NCT03655002

ACTIVE NOT RECRUITING Phase 1

Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

NCT03598998

ACTIVE NOT RECRUITING Phase 2

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

NCT03671811

ACTIVE NOT RECRUITING Phase 1

A Blood Stem Cell Transplant for Sickle Cell Disease

NCT03249831

ACTIVE NOT RECRUITING Phase 2

Brentuximab Vedotin and Nivolumab in Treating Patients With Early Stage Classic Hodgkin Lymphoma

NCT03712202

ACTIVE NOT RECRUITING

Blood Samples to Identify Biomarkers in Patients Treated With Cyclophosphamide After Donor Stem Cell Transplant

NCT04160390

ACTIVE NOT RECRUITING NA

Multimedia Self-Management Intervention for Lung Cancer Surgery Family Caregivers and Patients

NCT03686007

ACTIVE NOT RECRUITING

Early Recovery After Surgery Protocol in Improving Quality of Life in Participants With Stage 0-IIIC Gastric Cancer Undergoing Surgery

NCT03997162

ACTIVE NOT RECRUITING Phase 1

Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease

NCT03664830

ACTIVE NOT RECRUITING Phase 1

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

NCT03696030

ACTIVE NOT RECRUITING Phase 2

Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer

NCT03361735

ACTIVE NOT RECRUITING Phase 1

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

NCT03560752

ACTIVE NOT RECRUITING Phase 1

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

NCT03389230

ACTIVE NOT RECRUITING Phase 1

Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma

NCT03479268

ACTIVE NOT RECRUITING NA

Eat, Move, Live Program for the Reduction of Cancer and Chronic Disease Risk in Underserved Communities

NCT05414396

ACTIVE NOT RECRUITING NA

High-Intensity Parent Intervention Program in Improving Learning and School Functioning in Latino Children With Acute Leukemia or Lymphoblastic Lymphoma

NCT03178617

ACTIVE NOT RECRUITING Phase 1

Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease

NCT03279094

← Previous Page 5 of 12 Next →

What the Pipeline for City of Hope Medical Center Shows

According to the ClinicalTrials.gov registry, City of Hope Medical Center is linked to 582 US clinical trials across every stage of research activity. Of those, 167 studies are currently recruiting, about 29% of the sponsor's indexed portfolio, and 217 are already marked complete, representing roughly 37% of the total.

The phase mix for City of Hope Medical Center reports 9 late-stage studies (Phase 3 and Phase 4 combined) and 382 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for City of Hope Medical Center is Acute Myeloid Leukemia with 22 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.