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NCT03865992 · ClinicalTrials.gov registry record · NA
Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease
A NA study of Breast Cancer and Joint Pain, sponsored by City of Hope Medical Center.
- Active
- Registry status
- NA
- Development phase
- 42
- Enrollment target
- 4
- Study locations
NCT03865992: Active NA study of Breast Cancer and Joint Pain, sponsored by City of Hope Medical Center.
NCT03865992 is a NA study of Breast Cancer and Joint Pain that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 42 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 4 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03865992, a NA study of Breast Cancer and Joint Pain, is active but no longer recruiting, sponsored by City of Hope Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
- 4
- Study locations
Study Summary
This phase I trial studies how well curcumin works in reducing joint pain in patients who are breast cancer survivors and have joint disease caused by treatment with aromatase inhibitors. Curcumin is an ingredient of turmeric, a plant in the ginger family, which is commonly used in curries and South Asian and Middle Eastern cooking, and may decrease joint pain in patients with arthritis from other conditions (such as osteoarthritis and rheumatoid arthritis).
Primary Outcome
The study will assess the feasibility of using the Functional Assessment of Cancer Therapy-Endocrine Symptoms (FACT-ES) to detect changes in aromatase inhibitor (AI)-induced symptoms and well-being in postmenopausal women with breast cancer randomized to 3 months of nanoemulsion curcumin (NEC) versus (vs) placebo capsules.
Conditions Studied
Interventions
- OTHER Quality-of-Life Assessment
- OTHER Placebo
- DIETARY_SUPPLEMENT Curcumin
- BEHAVIORAL Questionnaire
- OTHER Nanoemulsion
Study Locations (4)
California
- City of Hope Medical Center - Duarte
- City of Hope Rancho Cucamonga - Rancho Cucamonga
- City of Hope South Pasadena - South Pasadena
Ohio
- Ohio State University Comprehensive Cancer Center - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2019-03-04 |
| Est. Completion | 2026-09-08 |
| Phase | NA |
What the registry record for NCT03865992 still lists
NCT03865992 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which Quality-of-Life Assessment is the first listed.
NCT03865992 reports a single indexed study location in California, Ohio.
Frequently Asked Questions
What is clinical trial NCT03865992 about?
NCT03865992 is a clinical study titled "Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease". This phase I trial studies how well curcumin works in reducing joint pain in patients who are breast cancer survivors and have joint disease caused by treatment with aromatase inhibitors. Curcumin is an ingredient of turmeric, a plant in the ginger family, which is commonly used in curries and South...
What is the current status of trial NCT03865992?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 42 participants. The study started on 2019-03-04. Estimated completion is 2026-09-08.
What conditions does trial NCT03865992 study?
This clinical trial studies the following conditions: Breast Cancer, Joint Pain.
What interventions are being tested in trial NCT03865992?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Placebo (OTHER), Curcumin (DIETARY_SUPPLEMENT), Questionnaire (BEHAVIORAL), Nanoemulsion (OTHER).
Who is sponsoring clinical trial NCT03865992?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03865992 being conducted?
This trial has 4 study locations across California, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03865992's enrollment target sits among peer trials
42 864th of 1224 higher than 356 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)
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A Randomized Controlled Trial (RCT) to Determine the Efficacy of a Multidisciplinary CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer Survivors
RECRUITING · NA
-
Precise Oncology Interventions in Nutrition and Training (OnPoint)
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