Children's Oncology Group

342 total trials 33 currently recruiting 260 completed

Children's Oncology Group sponsors 342 registered US clinical trials on ClinicalTrials.gov, 33 of them currently recruiting, and 260 completed. 103 of these trials are in Phase 3-4 (later-stage) and 128 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Leukemia, with 12 trials.

Trial Pipeline

342 total, page 3 of 7

COMPLETED

Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas

NCT01793233

COMPLETED Phase 1

Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

NCT01606878

COMPLETED Phase 1

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

NCT01798004

COMPLETED Phase 3

Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant

NCT01503515

COMPLETED

Biomarker Differences in Samples From Patients With Undifferentiated Sarcomas

NCT01802125

COMPLETED

Genetic Biomarkers in Saliva Samples From Patients With Ewing Sarcoma

NCT01876303

COMPLETED

Studying Biomarkers in Samples From Younger Patients With Acute Myeloid Leukemia

NCT01642121

COMPLETED

Biomarkers in Patients With Advanced Rhabdomyosarcoma

NCT01668095

COMPLETED

Studying Genes in Samples From Younger Patients With Acute Megakaryoblastic Leukemia

NCT01642069

COMPLETED Phase 2

Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

NCT01602666

COMPLETED

Studying Genes Associated With Non-Hodgkin Lymphoma in Young Patients

NCT01623856

COMPLETED

Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia

NCT01625143

COMPLETED

Studying Protein Expression in Tissue Samples From Younger Patients With Rhabdomyosarcoma

NCT01609803

COMPLETED

Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With Rhabdomyosarcoma

NCT01626170

COMPLETED

Studying Biomarkers in Urine Samples From Younger Patients With Wilms Tumor

NCT01614808

COMPLETED

Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia

NCT01576185

COMPLETED NA

Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their Parents

NCT01556256

COMPLETED

Studying Chromosomes in Samples From Younger Patients With Neuroblastoma

NCT01589341

COMPLETED

Study of Tumor Samples From Patients With Ependymoma Treated on the Children's Oncology Group ACNS0121 Trial

NCT01407744

COMPLETED

Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic Leukemia

NCT01540578

COMPLETED Phase 1

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

NCT01175356

COMPLETED

Biomarkers in Tumor Tissue Samples From Younger Patients With Rhabdomyosarcoma

NCT01496573

COMPLETED

Biomarkers in Samples From Younger Patients With Wilms Tumor

NCT01493817

COMPLETED

DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings

NCT01434355

COMPLETED Phase 3

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

NCT01371656

COMPLETED Phase 2

Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma

NCT01334515

COMPLETED

Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma

NCT01374672

COMPLETED

Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma

NCT01358617

COMPLETED Phase 1

Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma

NCT01273090

COMPLETED Phase 3

Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia

NCT01307579

COMPLETED

Biomarkers in Tissue Samples From Young Patients With Liver Cancer

NCT01336881

COMPLETED Phase 3

Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant

NCT01305200

COMPLETED Phase 2

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

NCT01154816

COMPLETED Phase 3

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma

NCT01231906

COMPLETED Phase 1

INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease

NCT01164163

COMPLETED

Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

NCT01142427

COMPLETED

DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma

NCT01190943

COMPLETED

Lestaurtinib With or Without Chemotherapy Agents in Samples From Young Patients With Leukemia

NCT01150669

COMPLETED Phase 3

Collection of Bone Marrow From Donors Treated With or Without Filgrastim

NCT01149096

COMPLETED

Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor

NCT01118078

COMPLETED

Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia

NCT01076569

COMPLETED

Genetic Biomarkers in Tissue Samples From Patients With Osteosarcoma

NCT01807143

COMPLETED Phase 3

Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma

NCT01026220

COMPLETED

Studying DNA in Blood and Bone Marrow Samples From Younger Patients With Acute Myeloid Leukemia

NCT01024127

COMPLETED

Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas

NCT01807052

COMPLETED

Gene Analysis in Studying Susceptibility to Wilms Tumor

NCT01808079

COMPLETED Phase 1

Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

NCT00939770

COMPLETED

Biomarkers in Bone Marrow Samples From Patients With Acute Promyelocytic Leukemia

NCT01146223

COMPLETED Phase 1

Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features

NCT01048892

COMPLETED

Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT01146210

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What the Pipeline for Children's Oncology Group Shows

According to the ClinicalTrials.gov registry, Children's Oncology Group is linked to 342 US clinical trials across every stage of research activity. Of those, 33 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 260 are already marked complete, representing roughly 76% of the total.

The phase mix for Children's Oncology Group reports 103 late-stage studies (Phase 3 and Phase 4 combined) and 128 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Children's Oncology Group is Leukemia with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.