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NCT01576185 · ClinicalTrials.gov registry record
Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia
A clinical trial, sponsored by Children's Oncology Group.
- Completed
- Registry status
- 10
- Enrollment target
NCT01576185: Completed study, sponsored by Children's Oncology Group.
NCT01576185 is a clinical trial that has completed, run by Children's Oncology Group. The registered enrollment target is 10 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01576185 has completed, sponsored by Children's Oncology Group.
- COMPLETED
- Registry status
- 10 participants
- Enrollment target
Study Summary
These laboratory trial studies the development and treatment of a mouse model for acute myeloid leukemia (AML) using samples from younger patients with AML. Studying tissue samples from patients with cancer in the laboratory may help doctors learn more about cancer and how well patients will respond to treatment.
Primary Outcome
We will measure total leukemic burden from harvested femurs, tibias, and spleen by quantitative flow cytometry, estimate engraftment, and describe 95% confidence intervals. The total AML cell count of the control and treatment cohorts will be compared using an analysis of variance (ANOVA) test.
Interventions
- OTHER laboratory biomarker analysis
- DRUG sorafenib tosylate
- DRUG quizartinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2012-05 |
| Est. Completion | 2016-05 |
What the finished NCT01576185 record still lists
NCT01576185 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target.
The record links to 0 conditions, and to 3 interventions - of which laboratory biomarker analysis is the first listed.
NCT01576185 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01576185 about?
NCT01576185 is a clinical study titled "Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia". These laboratory trial studies the development and treatment of a mouse model for acute myeloid leukemia (AML) using samples from younger patients with AML. Studying tissue samples from patients with cancer in the laboratory may help doctors learn more about cancer and how well patients will respond...
What is the current status of trial NCT01576185?
This trial is currently completed. The enrollment target is 10 participants. The study started on 2012-05. Estimated completion is 2016-05.
What interventions are being tested in trial NCT01576185?
The interventions under investigation include: laboratory biomarker analysis (OTHER), sorafenib tosylate (DRUG), quizartinib (DRUG).
Who is sponsoring clinical trial NCT01576185?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
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