Children's Hospital of Philadelphia

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Children's Hospital of Philadelphia sits in the top decile of US sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count).

431 total trials 78 currently recruiting 300 completed early-phase tilt top decile by trial count

Children's Hospital of Philadelphia: 431 sponsored US clinical trials, 78 recruiting.

Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.

Top-decile sponsor footprint

Children's Hospital of Philadelphia ranks in the top decile of sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 65/100

300 of 333 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

431 total, page 9 of 9

COMPLETED NA

Comparison of Three Therapy-Based Interventions for Preventing Depression in Adolescents

NCT00258752

COMPLETED Phase 1

Effect of Family-Based Prevention on Children of Depressed Parents

NCT00183365

TERMINATED

Thyroid Hormones in Critically Ill Children

NCT00664079

COMPLETED Phase 1

Safety Study of Elidel (Pimecrolimus) 1% Cream to Treat Netherton Syndrome

NCT00208026

TERMINATED Phase 4

Efficacy Study of Continuous Intraarticular Infusion in Patients Undergoing Arthroscopic Knee and Shoulder Operations

NCT00314457

COMPLETED Phase 4

Transthecal Metacarpal Block Versus Traditional Digital Block for Painful Finger Procedures in Children

NCT00130104

COMPLETED Phase 3

Effects of Additional Fentanyl to Epidural Bupivacaine for Post-Thoracotomy Pain in Neonates

NCT00286143

COMPLETED Phase 2

CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell Depletion

NCT00579124

COMPLETED NA

Trial Regarding the Acceptability of Audiotape Intimate Partner Violence (IPV) Screening

NCT00122395

TERMINATED

Structural Brain Abnormalities in Children Born Prematurely: New Detection Methods and Clinical-Pathological Correlates

NCT00153855

COMPLETED Phase 2

Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism

NCT00674440

COMPLETED NA

Philadelphia Preterm Prevention Project

NCT01117922

COMPLETED

Dysrhythmias During General Anesthesia in Children

NCT00715390

COMPLETED Phase 4

Combination Therapy for Atopic Dermatitis

NCT00119158

COMPLETED Phase 3

Preventing Youth Suicide in Primary Care: A Family Model

NCT00604097

COMPLETED Phase 4

Study of the Effects of Osmotic-Release Oral System (OROS) Methylphenidate (Concerta) on Attention and Memory

NCT00530257

TERMINATED Phase 4

Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease

NCT00252122

COMPLETED Phase 4

Continuous Levalbuterol for Treatment of Status Asthmaticus in Children

NCT00124176

COMPLETED Phase 3

The MOM Program: 5 Year Follow-up Study of a Home Visiting Program at The Children's Hospital of Philadelphia

NCT00231179

COMPLETED NA

Educational Video for Improving Follow-up After an Emergency Department Visit for Asthma

NCT00113633

COMPLETED NA

Nasal Potential Difference (NPD) for the Diagnosis of Cystic Fibrosis

NCT00589745

TERMINATED Phase 1

Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis)

NCT00590538

TERMINATED Phase 1

Sirolimus in Treating Young Patients With Relapsed or Refractory Acute Leukemia or Non-Hodgkin's Lymphoma

NCT00068302

TERMINATED NA

Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma

NCT00060008

COMPLETED NA

Effects of Head Elevation on Intracranial Pressure in Children

NCT00636376

COMPLETED Phase 3

The MOM Program at the Children's Hospital of Philadelphia

NCT00230555

TERMINATED Phase 2

Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma

NCT00031590

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

NCT00030264

COMPLETED Phase 3

Nitric Oxide Administration for Acute Respiratory Distress Syndrome

NCT00240487

TERMINATED Phase 1

Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

NCT00031577

TERMINATED Phase 3

Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia

NCT00002961

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What is open in the Children's Hospital of Philadelphia pipeline

78 recruiting of 431 indexed (18% open); 300 completed (70%).

Phase mix: 35 late (III/IV) vs 81 early (I/II) (early-phase heavy).

Top condition: Pediatric Cancer (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Children's Hospital of Philadelphia: open-pipeline peers nationwide

Peers matched on 431 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share Children's Hospital of PhiladelphiaNovo Nordisk A/SUniversity of Illinois at ChicagoVanderbilt UniversityDartmouth-Hitchcock Medical CenterWeill Medical College of Cornell UniversityUniversity of California, BerkeleyGeorge Washington UniversityHospital for Special Surgery, New York
Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 431 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Children's Hospital of Philadelphia page

431 registered trials is a research-attention snapshot, not an endorsement of Children's Hospital of Philadelphia or any single study.

  • 78 of Children's Hospital of Philadelphia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Pediatric Cancer is the condition Children's Hospital of Philadelphia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pediatric Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Children's Hospital of Philadelphia pipeline card: 431 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.