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NCT00579124 · ClinicalTrials.gov registry record · Phase 2
CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell Depletion
A Phase 2 study, sponsored by Children's Hospital of Philadelphia.
- Completed
- Registry status
- Phase 2
- Development phase
- 93
- Enrollment target
NCT00579124: Completed Phase 2 study, sponsored by Children's Hospital of Philadelphia.
NCT00579124 is a Phase 2 study that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 93 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00579124, a Phase 2 study, has completed, sponsored by Children's Hospital of Philadelphia.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 93 participants
- Enrollment target
Study Summary
This is a pilot study with 2 strata to evaluate engraftment and graft vs. host disease (GVHD) in patients receiving unrelated or partially matched related donor peripheral stem cells using the CliniMACS system to positively deplete T cells to prevent severe GVHD. Feasibility will be tested, focusing on engraftment, treatment-related mortality (with a specific focus on interstitial pneumonitis) and severe GVHD.
Primary Outcome
Successful engraftment will be whether subjects have achieved an absolute neutrophil count (ANC) \>500 and platelet count \>20 x 109/l by 100 days after transplant
Interventions
- DEVICE CliniMACs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 93 participants |
| Start Date | 2005-01 |
| Est. Completion | 2017-12-30 |
| Phase | Phase 2 |
What the finished NCT00579124 record still lists
NCT00579124 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 93 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (30% lower).
The record links to 0 conditions, and to 1 intervention - of which CliniMACs is the first listed.
NCT00579124 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00579124 about?
NCT00579124 is a clinical study titled "CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell Depletion". This is a pilot study with 2 strata to evaluate engraftment and graft vs. host disease (GVHD) in patients receiving unrelated or partially matched related donor peripheral stem cells using the CliniMACS system to positively deplete T cells to prevent severe GVHD. Feasibility will be tested, focusing...
What is the current status of trial NCT00579124?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 93 participants. The study started on 2005-01. Estimated completion is 2017-12-30.
What interventions are being tested in trial NCT00579124?
The interventions under investigation include: CliniMACs (DEVICE).
Who is sponsoring clinical trial NCT00579124?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00579124's enrollment target sits among peer trials
93 766th of 2000 higher than 1,234 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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