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NCT00240487 · ClinicalTrials.gov registry record · Phase 3
Nitric Oxide Administration for Acute Respiratory Distress Syndrome
A Phase 3 study, sponsored by Children's Hospital of Philadelphia.
- Completed
- Registry status
- Phase 3
- Development phase
- 52
- Enrollment target
NCT00240487: Completed Phase 3 study, sponsored by Children's Hospital of Philadelphia.
NCT00240487 is a Phase 3 study that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 52 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00240487, a Phase 3 study, has completed, sponsored by Children's Hospital of Philadelphia.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 52 participants
- Enrollment target
Study Summary
This research project is an open-label, randomized study for the use of Nitric Oxide in pediatric patients with acute respiratory distress syndrome (ARDS). The study examines whether nitric oxide (NO) treatment impacts the the P:F ratio (arterial partial pressure of oxygen (PaO2) divided by fraction of inspired oxygen (FiO2) in patients with ARDS. The goal of the study is to evaluate whether the order of NO therapy will have any effect on response, and evaluate the characteristics of patients who respond to NO compared to those who do not.
Primary Outcome
Arterial blood gas measurements with cooximetry to evaluate arterial partial pressure of oxygen (PaO2) and fraction of inspired oxygen (FiO2) ratio. The mean PaO2/FiO2 ratio for each group after completion 8 hour of study participation was compared
Interventions
- OTHER No Intervention
- DRUG Nitric Oxide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2000-09 |
| Est. Completion | 2008-09 |
| Phase | Phase 3 |
What the finished NCT00240487 record still lists
NCT00240487 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which No Intervention is the first listed.
NCT00240487 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00240487 about?
NCT00240487 is a clinical study titled "Nitric Oxide Administration for Acute Respiratory Distress Syndrome". This research project is an open-label, randomized study for the use of Nitric Oxide in pediatric patients with acute respiratory distress syndrome (ARDS). The study examines whether nitric oxide (NO) treatment impacts the the P:F ratio (arterial partial pressure of oxygen (PaO2) divided by fraction...
What is the current status of trial NCT00240487?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 52 participants. The study started on 2000-09. Estimated completion is 2008-09.
What interventions are being tested in trial NCT00240487?
The interventions under investigation include: No Intervention (OTHER), Nitric Oxide (DRUG).
Who is sponsoring clinical trial NCT00240487?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00240487's enrollment target sits among peer trials
52 1841st of 2000 higher than 159 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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