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NCT01821300 · ClinicalTrials.gov registry record
Down Syndrome Metabolic Health Study
A clinical trial of Down Syndrome and Trisomy 21, sponsored by Children's Hospital of Philadelphia.
- Completed
- Registry status
- 257
- Enrollment target
- 2
- Study locations
NCT01821300: Completed study of Down Syndrome and Trisomy 21, sponsored by Children's Hospital of Philadelphia.
NCT01821300 is a study of Down Syndrome and Trisomy 21 that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 257 participants, below the 2,467-participant average among 54 other Down Syndrome trials with a reported enrollment target (90% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01821300, a study of Down Syndrome and Trisomy 21, has completed, sponsored by Children's Hospital of Philadelphia.
- COMPLETED
- Registry status
- 257 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this research study is to determine which measures best capture cardiovascular disease (CVD) risk and type 2 diabetes (T2DM) risk in children and adolescents with Down syndrome (DS). We hypothesize that DS is associated with worse cardiometabolic risk factors for a given body mass index compared to controls. This difference arises at least in part, from increased fat tissue.
Primary Outcome
Non-HDL cholesterol measured via fasting blood draw
Conditions Studied
Study Locations (2)
District of Columbia
- Children's National Medical Center - Washington D.C.
Pennsylvania
- The Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 257 participants |
| Start Date | 2013-02 |
| Est. Completion | 2017-08-25 |
What the finished NCT01821300 record still lists
NCT01821300 is an observational study that tracks outcomes without assigning an intervention. The registered 257 participants enrollment target is mid-sized for trials with a published cap, below the 2,467-participant average among 54 other Down Syndrome trials with a reported enrollment target (90% lower).
The record links to 2 conditions, with Down Syndrome appearing as the primary indexed condition, and to 0 interventions.
NCT01821300 reports a single indexed study location in District of Columbia, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01821300 about?
NCT01821300 is a clinical study titled "Down Syndrome Metabolic Health Study". The purpose of this research study is to determine which measures best capture cardiovascular disease (CVD) risk and type 2 diabetes (T2DM) risk in children and adolescents with Down syndrome (DS). We hypothesize that DS is associated with worse cardiometabolic risk factors for a given body mass in...
What is the current status of trial NCT01821300?
This trial is currently completed. The enrollment target is 257 participants. The study started on 2013-02. Estimated completion is 2017-08-25.
What conditions does trial NCT01821300 study?
This clinical trial studies the following conditions: Down Syndrome, Trisomy 21.
Who is sponsoring clinical trial NCT01821300?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01821300 being conducted?
This trial has 2 study locations across District of Columbia, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Down Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01821300's enrollment target sits among peer trials
257 18th of 54 higher than 37 of 54 other Down Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Down Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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