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NCT03109613 · ClinicalTrials.gov registry record · Phase 1
PEEP and V/Q Mismatch in Premature Infants
A Phase 1 study, sponsored by Children's Hospital of Philadelphia.
- Terminated
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT03109613: Clinical Trial Phase 1 study, sponsored by Children's Hospital of Philadelphia.
NCT03109613 is a Phase 1 study that was terminated before completion, run by Children's Hospital of Philadelphia. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03109613, a Phase 1 study, was terminated before completion, sponsored by Children's Hospital of Philadelphia.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
Positive end-expiratory pressure (PEEP) is used in premature infants receiving mechanical ventilation to maintain lungs open and facilitate gas exchange. When ventilation/perfusion mismatch is present, areas of the lung that are open for gas exchange do not match up with areas of the lung that are receiving blood for gas exchange. This study measures the feasibility of enrolling and completing study maneuvers in premature infants for a prospective study measuring the responsiveness of V/Q mismatch to changes in the amount (or level) of PEEP.
Primary Outcome
Rate of successfully study enrollment and completion
Interventions
- DEVICE Positive end-expiratory pressure (PEEP)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2016-04-11 |
| Est. Completion | 2018-08-08 |
| Phase | Phase 1 |
Why NCT03109613 stopped before completion
NCT03109613 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 1 intervention - of which Positive end-expiratory pressure (PEEP) is the first listed.
NCT03109613 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03109613 about?
NCT03109613 is a clinical study titled "PEEP and V/Q Mismatch in Premature Infants". Positive end-expiratory pressure (PEEP) is used in premature infants receiving mechanical ventilation to maintain lungs open and facilitate gas exchange. When ventilation/perfusion mismatch is present, areas of the lung that are open for gas exchange do not match up with areas of the lung that are r...
What is the current status of trial NCT03109613?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2016-04-11. Estimated completion is 2018-08-08.
What interventions are being tested in trial NCT03109613?
The interventions under investigation include: Positive end-expiratory pressure (PEEP) (DEVICE).
Who is sponsoring clinical trial NCT03109613?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03109613's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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