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COMPLETED Phase 2

Study of ARO-ANG3 in Adults With Mixed Dyslipidemia

NCT04832971 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of AROANG3-2001 is to evaluate the efficacy and safety of ARO-ANG3 in participants with mixed dyslipidemia. Participants will initially receive 2 subcutaneous injections of ARO-ANG3 or placebo. Participants who complete the double-blind treatment period may opt to continue in an open-label extension during which they will receive up to 8 doses of ARO-ANG3.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG ARO-ANG3

Study Locations (20)

Florida

  • Research Site 7 — Hialeah
  • Research Site 17 — Miami
  • Research Site 8 — Port Orange

Other

  • Research Site 18 — Nedlands
  • Research Site 12 — Québec
  • Research Site 9 — Québec

North Carolina

  • Research Site 15 — Greensboro
  • Research Site 2 — Morehead City

California

  • Research Site 5 — Huntington Park

Minnesota

  • Research Site 24 — Minneapolis

Nebraska

  • Research Site 10 — Omaha

Nevada

  • Research Site 23 — Las Vegas

New York

  • Research Site 22 — New York

Trial Details

FieldValue
Enrollment Target 204 participants
Start Date 2021-06-28
Est. Completion 2024-09-25
Phase Phase 2

Sponsor

Arrowhead Pharmaceuticals

11 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04832971

The ClinicalTrials.gov registry entry for NCT04832971 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 204 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Arrowhead Pharmaceuticals, which has 11 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Mixed Dyslipidemia appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04832971 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Florida, Other, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04832971 about?

NCT04832971 is a clinical study titled "Study of ARO-ANG3 in Adults With Mixed Dyslipidemia". The purpose of AROANG3-2001 is to evaluate the efficacy and safety of ARO-ANG3 in participants with mixed dyslipidemia. Participants will initially receive 2 subcutaneous injections of ARO-ANG3 or placebo. Participants who complete the double-blind treatment period may opt to continue in an open-lab...

What is the current status of trial NCT04832971?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 204 participants. The study started on 2021-06-28. Estimated completion is 2024-09-25.

What conditions does trial NCT04832971 study?

This clinical trial studies the following conditions: Mixed Dyslipidemia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04832971?

The interventions under investigation include: Placebo (DRUG), ARO-ANG3 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04832971?

This trial is sponsored by Arrowhead Pharmaceuticals, which has 11 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04832971 being conducted?

This trial has 20 study locations across California, Florida, Minnesota, Nebraska, Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial