Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Von Hippel-Lindau Disease: early-phase trial registry
4 of 6 indexed Von Hippel-Lindau Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 4 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Von Hippel-Lindau Disease: 6 US clinical trials tracked, 4 recruiting.
Von Hippel-Lindau Disease is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Joshua Mann, MPH, running 1 of these trials.
Enrollment posture brief
Registry condition von-hippel-lindau-disease
OPEN 4 | RECR 67% | LATE 0 | EARLY 3 | RANK #2866 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Adenocarcinoma of Lung (67% recruiting · 6 trials)
Von Hippel-Lindau Disease lists 4 open slots (67% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Von Hippel-Lindau Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Von Hippel-Lindau Disease is recruiting above its size-band peers.
4 of 6 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Von Hippel-Lindau Disease research.
Joshua Mann, MPH accounts for 1 of 6 trials (16.7%). 6 distinct sponsors appear on at least one study for this condition label.
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Typical Von Hippel-Lindau Disease enrolment sits around 322 participants.
Median target enrolment is 322 among the 6 trials that report a genuine target (sentinel values excluded). 2 of those (33.3%) plan for fewer than 100 participants.
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Von Hippel-Lindau Disease splits between interventional and observational designs.
3 interventional and 3 observational studies make up this index (50% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
MyVHL: Patient Natural History Study
Joshua Mann, MPH
NCT03749980
Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
National Cancer Institute (NCI)
NCT04074135
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Merck Sharp & Dohme
NCT04924075
Data Collection Protocol for Patients With Von Hippel Lindau Disease
M.D. Anderson Cancer Center
NCT05955014
Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma
National Eye Institute (NEI)
NCT04458935
Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only)
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02108002
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Von Hippel-Lindau Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Von Hippel-Lindau Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Von Hippel-Lindau Disease page
6 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Von Hippel-Lindau Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Joshua Mann, MPH sponsors the most Von Hippel-Lindau Disease trials on record, review their full trial history before evaluating a specific study. See Joshua Mann, MPH's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Von Hippel-Lindau Disease condition card totals 6 registered trials; most-linked intervention 68-Gallium DOTATATE; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.