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NCT06431373 · ClinicalTrials.gov registry record · Phase 3
A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis
A Phase 3 study of Uveitis and Uveitis, Posterior, sponsored by Priovant Therapeutics.
- Active
- Registry status
- Phase 3
- Development phase
- 371
- Enrollment target
- 20
- Study locations
NCT06431373: Active Phase 3 study of Uveitis and Uveitis, Posterior, sponsored by Priovant Therapeutics.
NCT06431373 is a Phase 3 study of Uveitis and Uveitis, Posterior that is active but no longer recruiting, run by Priovant Therapeutics. The registered enrollment target is 371 participants, below the 598-participant average among 19 other Uveitis trials with a reported enrollment target (38% lower). The trial reports 20 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06431373, a Phase 3 study of Uveitis and Uveitis, Posterior, is active but no longer recruiting, sponsored by Priovant Therapeutics.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 371 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to determine the safety and efficacy of brepocitinib in participants with active, non-anterior (intermediate, posterior, or pan) non-infectious uveitis (NIU).
Conditions Studied
Interventions
- DRUG Brepocitinib PO QD
- DRUG Placebo PO QD
Study Locations (20)
California
- Clinical Trial Site - Bakersfield
- Clinical Trial Site - Beverly Hills
- Clinical Trial Site - Fullerton
- Clinical Trial Site - Irvine
- Clinical Trial Site - La Jolla
- Clinical Trial Site - Los Angeles
- Clinical Trial Site - Los Angeles
- Clinical Trial Site - Modesto
- Clinical Trial Site - Sacramento
Arizona
- Clinical Trial Site - Phoenix
- Clinical Trial Site - Phoenix
Colorado
- Clinical Trial Site - Aurora
- Clinical Trial Site - Denver
Florida
- Clinical Trial Site - Fort Lauderdale
- Clinical Trial Site - St. Petersburg
Illinois
- Clinical Trial Site - Chicago
- Clinical Trial Site - Oak Park
Indiana
- Clinical Trial Site - Carmel
Kansas
- Clinical Trial Site - Prairie Village
Maryland
- Clinical Trial Site - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 371 participants |
| Start Date | 2024-09-11 |
| Est. Completion | 2028-02-01 |
| Phase | Phase 3 |
What the registry record for NCT06431373 still lists
NCT06431373 is an interventional study that assigns participants to a tested intervention. The registered 371 participants enrollment target is mid-sized for trials with a published cap, below the 598-participant average among 19 other Uveitis trials with a reported enrollment target (38% lower).
The record links to 3 conditions, with Uveitis appearing as the primary indexed condition, and to 2 interventions - of which Brepocitinib PO QD is the first listed.
NCT06431373 names 20 study sites across 8 states, led by California, Arizona, Colorado.
Frequently Asked Questions
What is clinical trial NCT06431373 about?
NCT06431373 is a clinical study titled "A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis". The purpose of this study is to determine the safety and efficacy of brepocitinib in participants with active, non-anterior (intermediate, posterior, or pan) non-infectious uveitis (NIU).
What is the current status of trial NCT06431373?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 371 participants. The study started on 2024-09-11. Estimated completion is 2028-02-01.
What conditions does trial NCT06431373 study?
This clinical trial studies the following conditions: Uveitis, Uveitis, Posterior, Uveitis, Intermediate.
What interventions are being tested in trial NCT06431373?
The interventions under investigation include: Brepocitinib PO QD (DRUG), Placebo PO QD (DRUG).
Who is sponsoring clinical trial NCT06431373?
This trial is sponsored by Priovant Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06431373 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Uveitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06431373's enrollment target sits among peer trials
371 5th of 19 higher than 15 of 19 other Uveitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Uveitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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