Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05286203 · ClinicalTrials.gov registry record · NA
Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing
A NA study of Uveitis and Infectious Disease, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05286203 is a NA study of Uveitis and Infectious Disease that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 100 participants, below the 612-participant average among 19 other Uveitis trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05286203, a NA study of Uveitis and Infectious Disease, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a multi-center randomized controlled evaluator-masked trial designed to compare metagenomic deep sequencing (MDS) versus standard of care testing for improvement of outcomes for intraocular infections. Patients with presumed intraocular infections who meet the eligibility criteria will be randomized to receive MDS testing results or not to receive MDS testing results. All patients will receive standard-of-care testing to guide management. Enrolled patients will be followed at week 2, week 3-6 (randomization visit), and at 4 weeks after the randomization visit. The proportions of patients who received the appropriate therapy and the proportions of patients with improved outcome will be compared between arms. Patient quality of life, MDS performance, and the provider certainly of belief will be collected.
Conditions Studied
Interventions
- DEVICE Metagenomic Deep Sequencing (MDS)
- DIAGNOSTIC_TEST Standard of Care (SOC)
Study Locations (1)
California
- University of California San Francisco (UCSF) - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-06-06 |
| Est. Completion | 2026-12 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05286203
The ClinicalTrials.gov registry entry for NCT05286203 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 612-participant average among 19 other Uveitis trials with a reported enrollment target (84% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Uveitis appearing as the primary indexed condition, and to 2 interventions - of which Metagenomic Deep Sequencing (MDS) is the first listed.
NCT05286203 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05286203 about?
NCT05286203 is a clinical study titled "Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing". This is a multi-center randomized controlled evaluator-masked trial designed to compare metagenomic deep sequencing (MDS) versus standard of care testing for improvement of outcomes for intraocular infections. Patients with presumed intraocular infections who meet the eligibility criteria will be ra...
What is the current status of trial NCT05286203?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2022-06-06. Estimated completion is 2026-12.
What conditions does trial NCT05286203 study?
This clinical trial studies the following conditions: Uveitis, Infectious Disease.
What interventions are being tested in trial NCT05286203?
The interventions under investigation include: Metagenomic Deep Sequencing (MDS) (DEVICE), Standard of Care (SOC) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05286203?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05286203 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Uveitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age
RECRUITING
-
Genetics of Uveitis
RECRUITING
-
Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography
RECRUITING
-
The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment
RECRUITING · Phase 3
-
Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
RECRUITING · Phase 1
-
Imaging Quantification of Inflammation (IQI)
ACTIVE NOT RECRUITING
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.