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Ulcerative Colitis (UC): early-phase trial registry
10 of 18 indexed Ulcerative Colitis (UC) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #953 of 28,707 conditions by registered trial count.
18 US clinical trials · 10 currently recruiting · #953 of 28,707 conditions by registered trial count
Ulcerative Colitis (UC): 18 US clinical trials tracked, 10 recruiting.
Ulcerative Colitis (UC) is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is AbbVie, running 5 of these trials.
Enrollment posture brief
Registry condition ulcerative-colitis-uc
OPEN 10 | RECR 56% | LATE 3 | EARLY 6 | RANK #953 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Acute Lymphoblastic Leukemia, Pediatric (56% recruiting · 9 trials)
Ulcerative Colitis (UC) lists 10 open slots (56% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Ulcerative Colitis (UC) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Ulcerative Colitis (UC) is recruiting above its size-band peers.
10 of 18 indexed trials (55.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Ulcerative Colitis (UC) research.
AbbVie accounts for 5 of 18 trials (27.8%). 13 distinct sponsors appear on at least one study for this condition label.
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Typical Ulcerative Colitis (UC) enrolment sits around 152 participants.
Median target enrolment is 152 among the 18 trials that report a genuine target (sentinel values excluded). 6 of those (33.3%) plan for fewer than 100 participants.
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Ulcerative Colitis (UC) research is mostly interventional.
13 interventional and 5 observational studies make up this index (72.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
18 total, page 1 of 1
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor
NCT06619990
Zymfentra (Infliximab-dyyb) REal World Cohort STudy
University of North Carolina, Chapel Hill
NCT07237516
STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission
University of Chicago
NCT06693310
Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies
Northwestern University
NCT07427017
Use of Psychologist-administered Cognitive Behavioral Therapy (CBT) or Self-administered CBT for the Treatment of Anxiety and/or Depression in Inflammatory Bowel Disease (IBD)
Yale University
NCT05377840
A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
Mirador Therapeutics
NCT07113522
Assessment and Educational Intervention to Reduce Ultra-processed Food Consumption in Pediatric Patients With IBD
Connecticut Children's Medical Center
NCT07224113
Evaluation of the SMART IBD App in Pediatric IBD
Children's Hospital Medical Center, Cincinnati
NCT07195123
Family Members At INcreased-risk for Developing Inflammatory Bowel Disease
Massachusetts General Hospital
NCT06655415
Evaluate the Safety, Tolerability, PK and PD of SAD of Intravenously Adminsterted ALTB-268 in Healthy Participants
AltruBio
NCT07350577
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
AbbVie
NCT01848561
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
AbbVie
NCT03398135
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
AbbVie
NCT03006068
Evaluating the Shift From Intravenous to Subcutaneous Vedolizumab for Inflammatory Bowel Disease
Vanderbilt University Medical Center
NCT07123350
Study to Evaluate the Safety and Efficacy of Two Adalimumab Dosing Regimens in Subjects With Moderate to Severe Ulcerative Colitis
AbbVie
NCT02065622
A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe it is in Participants With Moderate to Severe Ulcerative Colitis Who Failed Prior Therapy
AbbVie
NCT03695185
Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis D
University of California, San Francisco
NCT01877577
Early Serum Infliximab Levels in Severe Ulcerative Colitis.
University of California, San Francisco
NCT01971814
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 3 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Ulcerative Colitis (UC) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Ulcerative Colitis (UC) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Ulcerative Colitis (UC) page
18 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 10 Ulcerative Colitis (UC) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- AbbVie sponsors the most Ulcerative Colitis (UC) trials on record, review their full trial history before evaluating a specific study. See AbbVie's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ulcerative Colitis (UC) condition card totals 18 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.