Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Type 1 Diabetes Mellitus: early-phase trial registry
25 of 113 indexed Type 1 Diabetes Mellitus trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #113 of 28,707 conditions by registered trial count.
113 US clinical trials · 25 currently recruiting · #113 of 28,707 conditions by registered trial count
Type 1 Diabetes Mellitus: 113 US clinical trials tracked, 25 recruiting.
Type 1 Diabetes Mellitus is the subject of 113 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of Virginia, running 9 of these trials.
Enrollment posture brief
Registry condition type-1-diabetes-mellitus
OPEN 25 | RECR 22% | LATE 19 | EARLY 38 | RANK #113 | SPON 9
Volume-matched condition peers
Nearest open-share peer: Acne (22% recruiting · 27 trials)
Type 1 Diabetes Mellitus lists 25 open slots (22% of 113 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 1 Diabetes Mellitus on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Type 1 Diabetes Mellitus is recruiting below its size-band peers.
25 of 113 indexed trials (22.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Type 1 Diabetes Mellitus trials is spread across many organizations.
University of Virginia accounts for 9 of 113 trials (8%). 67 distinct sponsors appear on at least one study for this condition label.
-
Most Type 1 Diabetes Mellitus trials plan to enrol fewer than 100 people.
Median target enrolment is 48 among the 113 trials that report a genuine target (sentinel values excluded). 80 of those (70.8%) plan for fewer than 100 participants.
-
Type 1 Diabetes Mellitus research is mostly interventional.
95 interventional and 18 observational studies make up this index (84.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
113 total, page 3 of 3
The Effect of Insulin Glulisine Compared With Insulin Aspart on Breakfast Post Prandial Glucose Levels in Prepubertal Children
Corewell Health West
NCT00913497
A Clinical Study of the Performance of a Glucose Blinding Protein-Based Continuous Glucose Monitor (GBP CGM)
University of Virginia
NCT01469715
T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs
University of California, San Francisco
NCT01210664
T1DM Immunotherapy Using Polyclonal Tregs + IL-2
Jeffrey Bluestone
NCT02772679
Development of an Advisory System for Glycemic Control During the Menstrual Cycle in Patient With Type 1 Diabetes
University of Virginia
NCT01653210
A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus
Brigham and Women's Hospital
NCT01421355
Physiologic Response to Glucagon at Varying Insulin Levels
Legacy Health System
NCT01483651
Implantable Antenna Sensors for Continuous Glucose Monitoring
University of Alabama at Birmingham
NCT00596323
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus
Eli Lilly and Company
NCT03849612
Evaluation of Coffee Therapy for Improvement of Renal Oxygenation
University of Colorado, Denver
NCT03878277
Feasibility Study Using Zone-MPC Controller, HMS and Technosphere® Insulin Inhalation System From MannnKind Corp
Sansum Diabetes Research Institute
NCT01874392
High Risk Youth With Poorly-controlled Diabetes
Washington University School of Medicine
NCT03680079
Low Dose Cyclosporin and Methotrexate Therapy in Diabetes
Georgetown University
NCT00905073
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 20 |
| Phase 2 | 18 |
| Phase 3 | 14 |
| Phase 4 | 5 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 1 Diabetes Mellitus records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 1 Diabetes Mellitus trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 1 Diabetes Mellitus page
113 registered trials, 25 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 25 Type 1 Diabetes Mellitus trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Virginia sponsors the most Type 1 Diabetes Mellitus trials on record, review their full trial history before evaluating a specific study. See University of Virginia's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 1 Diabetes Mellitus condition card totals 113 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.