Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Systemic Sclerosis (SSc): early-phase trial registry
9 of 9 indexed Systemic Sclerosis (SSc) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 9 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Systemic Sclerosis (SSc): 9 US clinical trials tracked, 9 recruiting.
Systemic Sclerosis (SSc) is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Robyn T. Domsic, MD, MPH, running 2 of these trials.
Enrollment posture brief
Registry condition systemic-sclerosis-ssc
OPEN 9 | RECR 100% | LATE 0 | EARLY 6 | RANK #1916 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)
Systemic Sclerosis (SSc) lists 9 open slots (100% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Systemic Sclerosis (SSc) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Systemic Sclerosis (SSc) is recruiting above its size-band peers.
9 of 9 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Systemic Sclerosis (SSc) research.
Robyn T. Domsic, MD, MPH accounts for 2 of 9 trials (22.2%). 8 distinct sponsors appear on at least one study for this condition label.
-
Most Systemic Sclerosis (SSc) trials plan to enrol fewer than 100 people.
Median target enrolment is 80 among the 9 trials that report a genuine target (sentinel values excluded). 7 of those (77.8%) plan for fewer than 100 participants.
-
Systemic Sclerosis (SSc) research is mostly interventional.
7 interventional and 2 observational studies make up this index (77.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Fate Therapeutics
NCT06308978
The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life
Robyn T. Domsic, MD, MPH
NCT06675344
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Artiva Biotherapeutics
NCT06991114
A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis
argenx
NCT06655155
Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)
Zura Bio
NCT06843239
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Kyverna Therapeutics
NCT07403188
Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
Yale University
NCT07228429
Intralesional Injection of STS in Treatment of Calcinosis
Robyn T. Domsic, MD, MPH
NCT06672822
TENS in Scleroderma
University of Michigan
NCT06646913
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Systemic Sclerosis (SSc) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Systemic Sclerosis (SSc) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Systemic Sclerosis (SSc) page
9 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 9 Systemic Sclerosis (SSc) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Robyn T. Domsic, MD, MPH sponsors the most Systemic Sclerosis (SSc) trials on record, review their full trial history before evaluating a specific study. See Robyn T. Domsic, MD, MPH's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Systemic Sclerosis (SSc) condition card totals 9 registered trials; most-linked intervention Sodium Thiosulfate (STS); top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.