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NCT06672822 · ClinicalTrials.gov registry record · Phase 2
Intralesional Injection of STS in Treatment of Calcinosis
A Phase 2 study of Dermatomyositis and Systemic Sclerosis (SSc), sponsored by Robyn T. Domsic, MD, MPH.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06672822 is a Phase 2 study of Dermatomyositis and Systemic Sclerosis (SSc) that is actively recruiting participants, run by Robyn T. Domsic, MD, MPH. The registered enrollment target is 20 participants, below the 484-participant average among 19 other Dermatomyositis trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06672822, a Phase 2 study of Dermatomyositis and Systemic Sclerosis (SSc), is actively recruiting participants, sponsored by Robyn T. Domsic, MD, MPH.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The specific objective of this study is to perform a small, open-label study to assess the safety and efficacy of intralesional, subcutaneous injection of STS on calcinosis symptoms and lesion size in systemic sclerosis (SSc), mixed connective tissue disease (MCTD) and dermatomyositis (DM) patients. Injection will be guided by ultrasound, lesion size assessed by ultrasound, and symptom burden by patient-reported outcome measures.
Conditions Studied
Interventions
- DRUG Sodium Thiosulfate (STS)
Study Locations (1)
Pennsylvania
- UPMC Arthritis and Autoimmunity Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-03-17 |
| Est. Completion | 2029-05-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06672822
The ClinicalTrials.gov registry entry for NCT06672822 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 19 other Dermatomyositis trials with a reported enrollment target (96% lower). The listed sponsor is Robyn T. Domsic, MD, MPH, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Dermatomyositis appearing as the primary indexed condition, and to 1 intervention - of which Sodium Thiosulfate (STS) is the first listed.
NCT06672822 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06672822 about?
NCT06672822 is a clinical study titled "Intralesional Injection of STS in Treatment of Calcinosis". The specific objective of this study is to perform a small, open-label study to assess the safety and efficacy of intralesional, subcutaneous injection of STS on calcinosis symptoms and lesion size in systemic sclerosis (SSc), mixed connective tissue disease (MCTD) and dermatomyositis (DM) patients....
What is the current status of trial NCT06672822?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2025-03-17. Estimated completion is 2029-05-01.
What conditions does trial NCT06672822 study?
This clinical trial studies the following conditions: Dermatomyositis, Systemic Sclerosis (SSc), Calcinosis, Mixed Connective Tissue Disease (MCTD).
What interventions are being tested in trial NCT06672822?
The interventions under investigation include: Sodium Thiosulfate (STS) (DRUG).
Who is sponsoring clinical trial NCT06672822?
This trial is sponsored by Robyn T. Domsic, MD, MPH, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06672822 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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