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NCT06843239 · ClinicalTrials.gov registry record · Phase 2
Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)
A Phase 2 study of Scleroderma and Systemic Sclerosis (SSc), sponsored by Zura Bio.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
- 20
- Study locations
NCT06843239 is a Phase 2 study of Scleroderma and Systemic Sclerosis (SSc) that is actively recruiting participants, run by Zura Bio. The registered enrollment target is 80 participants, below the 399-participant average among 23 other Scleroderma trials with a reported enrollment target (80% lower). The trial reports 20 study locations across 9 states.
The verdict
NCT06843239, a Phase 2 study of Scleroderma and Systemic Sclerosis (SSc), is actively recruiting participants, sponsored by Zura Bio.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
- 20
- Study locations
Study Summary
The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 24 weeks (Period 1) in adult participants with systemic sclerosis, followed by an open-label extension period where all active participants will receive tibulizumab and will be evaluated for an additional 28 weeks (Period 2)
Conditions Studied
Interventions
- OTHER Placebo
- BIOLOGICAL Tibulizumab
Study Locations (20)
Other
- Organización Médica de Investigación - Buenos Aires
- Centro de Investigación y Prevención Cardiovascular-Arenales - Buenos Aires
- Hospital General de Agudos Dr. José María Ramos Mejia - Buenos Aires
- Instituto de Investigación Clínica TyT - Buenos Aires
- Centro Medico de Estudios Clinicos y Farmacovigilancia (CECYF) - Buenos Aires
- Consultorios Médicos Dr. Doreski - Buenos Aires
- Consultora Integral de Salud Centro Médico Privado - Córdoba
- Instituto CER S.A. - Quilmes
- AES - AS - Clinica Mayo de Urgencias - San Miguel de Tucumán
- CTR Estudios Clinicos - Santiago
- Enroll SpA - Santiago
- Centro de especialidades médicas Vanguardia - Temuco
California
- UCSD Altman Clinical and Translational Research Institute Center for Clinical Research - La Jolla
Florida
- IRIS Research and Development LLC - Plantation
Iowa
- University of Iowa - Iowa City
Massachusetts
- Massachusetts General Hospital - Boston
Michigan
- University of Michigan Hospital - Ann Arbor
Texas
- Rheumatology Associates - Arlington
Buenos Aires
- STAT Research S.A. - Buenos Aires
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-02-06 |
| Est. Completion | 2028-01 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06843239
The ClinicalTrials.gov registry entry for NCT06843239 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 399-participant average among 23 other Scleroderma trials with a reported enrollment target (80% lower). The listed sponsor is Zura Bio, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Scleroderma appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06843239 reports 20 study locations spanning 9 distinct geographic areas - top geographies include Other, California, Florida.
Frequently Asked Questions
What is clinical trial NCT06843239 about?
NCT06843239 is a clinical study titled "Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)". The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 24 weeks (Period 1) in adult participants with systemic sclerosis, followed by an open-label extension period where all active participants will receive tibulizumab an...
What is the current status of trial NCT06843239?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2025-02-06. Estimated completion is 2028-01.
What conditions does trial NCT06843239 study?
This clinical trial studies the following conditions: Scleroderma, Systemic Sclerosis (SSc).
What interventions are being tested in trial NCT06843239?
The interventions under investigation include: Placebo (OTHER), Tibulizumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT06843239?
This trial is sponsored by Zura Bio, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06843239 being conducted?
This trial has 20 study locations across California, Florida, Iowa, Massachusetts, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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