Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00389467 · ClinicalTrials.gov registry record · Phase 2
Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy
A Phase 2 study of Stroke, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- Phase 2
- Development phase
- 127
- Enrollment target
- 20
- Study locations
NCT00389467: Completed Phase 2 study of Stroke, sponsored by University of California, Los Angeles.
NCT00389467 is a Phase 2 study of Stroke that has completed, run by University of California, Los Angeles. The registered enrollment target is 127 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00389467, a Phase 2 study of Stroke, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 127 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare the effectiveness of treating acute ischemic stroke with mechanical embolectomy using the Merci Retriever or the Penumbra System within 8 hours of symptom onset to standard medical treatment, and to identify people who might benefit from mechanical embolectomy by the appearance of stroke on multimodal computerized tomography (CT) or magnetic resonance (MR) imaging.
Primary Outcome
Scale name is provided (Modified Rankin Scale) which is a standard measure of functional neurologic outcome in stroke. The scale runs from 0-6, running from perfect health without symptoms to death. * 0 - No symptoms. * 1 - No significant disability. Able to carry out all usual activities, despite some symptoms. * 2 - Slight disability. Able to look after own affairs without assistance, but unable to carry out all previous activities. * 3 - Moderate disability. Requires some help, but able to w
Conditions Studied
Interventions
- DEVICE Merci Retriever and Penumbra System
Study Locations (20)
California
- University of California at Los Angeles, UCLA Stroke Network, 924 Westwood Blvd #300 - Los Angeles
- Kaiser Permanente Los Angeles Medical Center 4867 W Sunset Blvd., Los Angeles CA 90027 - Los Angeles
- Cedars Sinai Medical Center 8700 Beverly Blvd., Los Angeles CA 90048 - Los Angeles
- University of California at San Diego, UCSD Medical Center, 200 W. Arbor Drive, OPC, 3rd Floor Suite 3 - San Diego
- Santa Monica-UCLA Medical Center, 1225 15th Street Santa Monica, CA 90404 - Santa Monica
District of Columbia
- Georgetown University, Georgetown University Hospital, Room GG012, Ground Floor Gorman, 3800 Reservoir Road, NW - Washington D.C.
- Washington Hospital Center, 110 Irving Street, NW, Washington, DC 20010 - Washington D.C.
Massachusetts
- Boston University, One Boston Medical Center Place, Department of Neurology, C329 - Boston
- Massachusetts General Hospital, 101 Huntington Ave Ste 300 - Boston
New York
- Cornell University, New York Presbyterian Hospital, Cornell Campus, 525 East 68th St, Box 141 - New York
- Columbia University, 710 W 168th St, NI 551, , - New York
Florida
- University of Miami 1400 NW 10th Street, 10th Floor, Miami FL 33136 - Miami
Iowa
- University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52242 - Iowa City
Maryland
- Suburban Hospital, 8600 Old Georgetown Road, Bethesda, MD 20814 - Bethesda
Missouri
- St. Louis University Hospital, 3635 Vista Avenue at Grand Boulevard Saint Louis, MO - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 127 participants |
| Start Date | 2004-05 |
| Est. Completion | 2012-04 |
| Phase | Phase 2 |
What the finished NCT00389467 record still lists
NCT00389467 is an interventional study that assigns participants to a tested intervention. The registered 127 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Merci Retriever and Penumbra System is the first listed.
NCT00389467 names 20 study sites across 13 states, led by California, District of Columbia, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00389467 about?
NCT00389467 is a clinical study titled "Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy". The purpose of this study is to compare the effectiveness of treating acute ischemic stroke with mechanical embolectomy using the Merci Retriever or the Penumbra System within 8 hours of symptom onset to standard medical treatment, and to identify people who might benefit from mechanical embolectomy...
What is the current status of trial NCT00389467?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 127 participants. The study started on 2004-05. Estimated completion is 2012-04.
What conditions does trial NCT00389467 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT00389467?
The interventions under investigation include: Merci Retriever and Penumbra System (DEVICE).
Who is sponsoring clinical trial NCT00389467?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00389467 being conducted?
This trial has 20 study locations across California, District of Columbia, Florida, Iowa, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00389467's enrollment target sits among peer trials
127 114th of 454 higher than 341 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
RECRUITING · Phase 2
-
Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia
RECRUITING · Phase 2
-
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
RECRUITING · Phase 2
-
Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors
RECRUITING · Phase 2
-
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
RECRUITING · Phase 2
-
Myofascial Dysfunction in Post Stroke Shoulder Pain
RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03017820 · 127 participants · Phase 1
A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma
- NCT03609580 · 127 participants · Phase 1
Post-operative Urinary Retention (POUR) Following Thoracic Surgery
- NCT06285643 · 127 participants · Phase 2
A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
- NCT06809400 · 127 participants · Phase 1
A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia