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ClinicalTrials.gov 5 recruiting now official registry

Smoking, Tobacco clinical trials

5 of 19 indexed Smoking, Tobacco trials are currently recruiting.

19 US clinical trials · 5 currently recruiting

Smoking, Tobacco is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Dana-Farber Cancer Institute, running 2 of these trials.

The research picture

Smoking, Tobacco has 19 registered US clinical trials, 5 of them open to new participants right now, about 26% of the total.

5
recruiting participants now
26%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Dana-Farber Cancer Institute
Phase 12Phase 31Phase 41

Active & Recent Trials

19 total, page 1 of 1

RECRUITING 5,122 participants

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Memorial Sloan Kettering Cancer Center

NCT06535867

RECRUITING NA 768 participants

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

University of Virginia

NCT05660525

RECRUITING Phase 3 400 participants

V+PSF-M for Tobacco Cessation in HIV Care in India

University of Colorado, Denver

NCT05786547

RECRUITING NA 50 participants

ACT Lung Health Intervention: Phase Two

Dana-Farber Cancer Institute

NCT06945120

RECRUITING NA 10 participants

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

Memorial Sloan Kettering Cancer Center

NCT06693700

ACTIVE NOT RECRUITING NA 153 participants

Digitally Enhanced Smoking Cessation for High Risk Smokers

Dana-Farber Cancer Institute

NCT04691297

ACTIVE NOT RECRUITING Phase 1 13 participants

Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction

University of Pennsylvania

NCT03442413

COMPLETED Phase 4 2,000 participants

The Whole Day First Grade Program

American Institutes for Research

NCT00257088

COMPLETED NA 1,944 participants

Helping Poor Smokers Quit

Washington University School of Medicine

NCT03194958

COMPLETED NA 165 participants

A Facebook Intervention for Young Sexual and Gender Minority Smokers

University of California, San Francisco

NCT03259360

COMPLETED NA 121 participants

A Guided Imagery Tobacco Cessation Intervention Delivered by a Quit Line and Website

University of Arizona

NCT02968381

COMPLETED NA 115 participants

Applying Novel Technologies and Methods to Inform the Ontology of Self-Regulation: Binge Eating and Smoking

Stanford University

NCT03353649

COMPLETED NA 100 participants

Tobacco Cessation Intervention

Barbara Ann Karmanos Cancer Institute

NCT03657511

COMPLETED Early Phase 1 99 participants

Hollings Cancer Center Varenicline Sampling Study

Medical University of South Carolina

NCT03742154

COMPLETED NA 95 participants

Personalized Feedback for Smokers With Elevated Anxiety Sensitivity

University of Houston

NCT03382093

COMPLETED NA 83 participants

Contingency Management for Smoking Cessation

University of California, San Francisco

NCT04982952

COMPLETED NA 61 participants

Connecting Alaska Native People to Quit Smoking

Mayo Clinic

NCT03645941

COMPLETED NA 21 participants

BRP1602: Evaluation of Technical and Logistical Feasibility to Measure Lung Permeability

RAI Services Company

NCT06105424

COMPLETED NA 18 participants

Tobacco Cessation in Public Housing

Johns Hopkins University

NCT04889638

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Smoking, Tobacco Trial Landscape

19 indexed Smoking, Tobacco studies · 5 recruiting (26%).

Phase mix: 2 late (III/IV) vs 2 early (I/II).

Top sponsor: Dana-Farber Cancer Institute (2 trials), 9 others listed. 19 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Smoking, Tobacco?

PlainTrial tracks 19 US clinical trials for Smoking, Tobacco, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Smoking, Tobacco?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.