Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06105424 · ClinicalTrials.gov registry record · NA
BRP1602: Evaluation of Technical and Logistical Feasibility to Measure Lung Permeability
A NA study of Smoking and Tobacco Use, sponsored by RAI Services Company.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
- 1
- Study location
NCT06105424: Completed NA study of Smoking and Tobacco Use, sponsored by RAI Services Company.
NCT06105424 is a NA study of Smoking and Tobacco Use that has completed, run by RAI Services Company. The registered enrollment target is 21 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06105424, a NA study of Smoking and Tobacco Use, has completed, sponsored by RAI Services Company.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
- 1
- Study location
Study Summary
This will be a single-center, single-blind, four-cohort, 22-day ambulatory study during which up to 24 healthy adult subjects \[6 smokers (SMK), 6 moist snuff consumers (MSC), 6 vapers (VAP), and 6 non-tobacco consumers (NTC)\] will complete 3 measurements of lung permeability. Nasal epithelial cells, sputum, and blood samples will also be collected for current and future biomarker research.
Primary Outcome
Assess the technical and logistical feasibility of conducting a clinical evaluation of lung permeability as a potential biomarker of effect of tobacco use.The outcome measure of this method development study: "the half-life (T 1/2) of inhaled 99mtechnetium diethylenetriaminepentaacetic acid (99mTC-DTPA) in lungs of study subjects by scintigraphy."
Conditions Studied
Interventions
- PROCEDURE Lung Permeability Assessment
Study Locations (1)
Nebraska
- Celerion, Inc. - Lincoln
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2016-09-24 |
| Est. Completion | 2016-12-28 |
| Phase | NA |
What the finished NCT06105424 record still lists
NCT06105424 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (95% lower).
The record links to 3 conditions, with Smoking appearing as the primary indexed condition, and to 1 intervention - of which Lung Permeability Assessment is the first listed.
NCT06105424 reports a single indexed study location in Nebraska.
Frequently Asked Questions
What is clinical trial NCT06105424 about?
NCT06105424 is a clinical study titled "BRP1602: Evaluation of Technical and Logistical Feasibility to Measure Lung Permeability". This will be a single-center, single-blind, four-cohort, 22-day ambulatory study during which up to 24 healthy adult subjects \[6 smokers (SMK), 6 moist snuff consumers (MSC), 6 vapers (VAP), and 6 non-tobacco consumers (NTC)\] will complete 3 measurements of lung permeability. Nasal epithelial cell...
What is the current status of trial NCT06105424?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2016-09-24. Estimated completion is 2016-12-28.
What conditions does trial NCT06105424 study?
This clinical trial studies the following conditions: Smoking, Tobacco Use, Smoking, Tobacco.
What interventions are being tested in trial NCT06105424?
The interventions under investigation include: Lung Permeability Assessment (PROCEDURE).
Who is sponsoring clinical trial NCT06105424?
This trial is sponsored by RAI Services Company, which has 42 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06105424 being conducted?
This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06105424's enrollment target sits among peer trials
21 115th of 123 higher than 8 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Clinical Alternatives for Reducing Harm Using E-cigarettes
RECRUITING · NA
-
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
RECRUITING · NA
-
Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network
RECRUITING · NA
-
Enhancing Motivation to Quit Smoking Via Self-Help Intervention Targeted to Cancer Type
RECRUITING · NA
-
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
RECRUITING · NA
-
Take A Break - Rural
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02447874 · 21 participants · Phase 1
Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease
- NCT03826992 · 21 participants · Phase 1
Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia
- NCT04107077 · 21 participants · Phase 2
Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer
- NCT04158635 · 21 participants · Phase 1
Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI