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ClinicalTrials.gov 14 recruiting now early-phase tilt

Smoking Behaviors: early-phase trial registry

14 of 22 indexed Smoking Behaviors trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #756 of 28,707 conditions by registered trial count.

22 US clinical trials · 14 currently recruiting · #756 of 28,707 conditions by registered trial count

Smoking Behaviors: 22 US clinical trials tracked, 14 recruiting.

Smoking Behaviors is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is RAI Services Company, running 3 of these trials.

Enrollment posture brief

Registry condition smoking-behaviors

OPEN 14 | RECR 64% | LATE 0 | EARLY 2 | RANK #756 | SPON 3

Nearest open-share peer: Autoimmune Disease (64% recruiting · 11 trials)

Smoking Behaviors (this)64%Advanced Melanoma63.6%Acute Myeloid Leukemia Arisi18.2%Adenocarcinoma of the Prosta0%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Smoking Behaviors

Smoking Behaviors lists 14 open slots (64% of 22 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Smoking Behaviors on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Smoking Behaviors is recruiting above its size-band peers.

    14 of 22 indexed trials (63.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Smoking Behaviors trials is spread across many organizations.

    RAI Services Company accounts for 3 of 22 trials (13.6%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Typical Smoking Behaviors enrolment sits around 194 participants.

    Median target enrolment is 194 among the 22 trials that report a genuine target (sentinel values excluded). 7 of those (31.8%) plan for fewer than 100 participants.

  4. Smoking Behaviors research is mostly interventional.

    20 interventional and 2 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12

Open and recent trials

22 total, page 1 of 1

RECRUITING 2,000 participants

Health Opportunities and Promoters of Equitable Screening for Lung Cancer

Massachusetts General Hospital

NCT05784922

RECRUITING NA 800 participants

Take A Break - Rural

Wake Forest University Health Sciences

NCT05790486

RECRUITING Phase 1 780 participants

Overcoming Nicotine Dependence to Enable Quitting

Rush University Medical Center

NCT05513872

RECRUITING NA 544 participants

A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse

Medical University of South Carolina

NCT06118502

RECRUITING NA 268 participants

Smoke Free SafeCare: Establishing a Smoke Free Home in CPS-involved Families

Georgia State University

NCT05000632

RECRUITING NA 256 participants

Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction

Yale University

NCT06077240

RECRUITING NA 225 participants

Switch or Quit R01

Medical University of South Carolina

NCT06373679

RECRUITING NA 160 participants

Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand

Roswell Park Cancer Institute

NCT07102082

RECRUITING 100 participants

Vape Use Among Younger & Older Smokers

Abramson Cancer Center at Penn Medicine

NCT07214168

RECRUITING Phase 1 55 participants

Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability

JT International

NCT07476144

RECRUITING NA 50 participants

ACT Lung Health Intervention: Phase Two

Dana-Farber Cancer Institute

NCT06945120

RECRUITING NA 40 participants

Abuse Liability for Five Modern Oral Nicotine Products

RAI Services Company

NCT07132814

RECRUITING NA 20 participants

rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings

West Virginia University

NCT06228235

RECRUITING NA 10 participants

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

Memorial Sloan Kettering Cancer Center

NCT06693700

ACTIVE NOT RECRUITING NA 153 participants

Digitally Enhanced Smoking Cessation for High Risk Smokers

Dana-Farber Cancer Institute

NCT04691297

ACTIVE NOT RECRUITING NA 23 participants

An Experimental Evaluation of Menthol-Flavored Tobacco Accessories

Virginia Polytechnic Institute and State University

NCT07092501

COMPLETED NA 1,973 participants

Interventions to Help More Low-income Smokers Quit

Washington University School of Medicine

NCT04311983

COMPLETED NA 663 participants

Tobacco/Nicotine Purchase Patterns Across SES

Virginia Polytechnic Institute and State University

NCT06795997

COMPLETED NA 658 participants

C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)

Case Comprehensive Cancer Center

NCT04358705

COMPLETED NA 194 participants

CSD210903: A Study to Determine Subject Puffing Patterns of a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in an Ambulatory Setting

RAI Services Company

NCT05307822

COMPLETED NA 171 participants

Cigarette Smoking Among Young Adults

University of Oklahoma

NCT04340947

COMPLETED NA 75 participants

CSD200907: A Study to Assess Elements of Abuse Liability for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants

RAI Services Company

NCT05114863

Phase Distribution

PhaseTrial count
Phase 1 2

Named interventions

Most-linked intervention names on Smoking Behaviors records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Product D Other
2 trials
Product C Other
2 trials
Product B Other
2 trials
Smoke Free Home Behavioral
1 trials
Product A2 Other
1 trials
Product A1 Other
1 trials
Very low nicotine cigarette: non-mentol Other
1 trials
Very low nicotine cigarette: menthol Other
1 trials

US sites by state

Facility locations filed on Smoking Behaviors trials. A trial with sites in several states counts in each.

Massachusetts 3 trials
Virginia 2 trials
Texas 2 trials
Tennessee 2 trials
South Carolina 2 trials
New York 2 trials
North Carolina 2 trials
Georgia 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Smoking Behaviors page

22 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Smoking Behaviors condition card totals 22 registered trials; most-linked intervention Product D; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.