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2026 data Public-data reference. official source

Smoking Behaviors

Open-data reference.

22 US clinical trials · 14 currently recruiting

Active & Recent Trials

RECRUITING 2,000 participants

Health Opportunities and Promoters of Equitable Screening for Lung Cancer

Massachusetts General Hospital

NCT05784922

RECRUITING NA 800 participants

Take A Break - Rural

Wake Forest University Health Sciences

NCT05790486

RECRUITING Phase 1 780 participants

Overcoming Nicotine Dependence to Enable Quitting

Rush University Medical Center

NCT05513872

RECRUITING NA 544 participants

A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse

Medical University of South Carolina

NCT06118502

RECRUITING NA 268 participants

Smoke Free SafeCare: Establishing a Smoke Free Home in CPS-involved Families

Georgia State University

NCT05000632

RECRUITING NA 256 participants

Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction

Yale University

NCT06077240

RECRUITING NA 225 participants

Switch or Quit R01

Medical University of South Carolina

NCT06373679

RECRUITING NA 160 participants

Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand

Roswell Park Cancer Institute

NCT07102082

RECRUITING 100 participants

Vape Use Among Younger & Older Smokers

Abramson Cancer Center at Penn Medicine

NCT07214168

RECRUITING Phase 1 55 participants

Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability

JT International

NCT07476144

RECRUITING NA 50 participants

ACT Lung Health Intervention: Phase Two

Dana-Farber Cancer Institute

NCT06945120

RECRUITING NA 40 participants

Abuse Liability for Five Modern Oral Nicotine Products

RAI Services Company

NCT07132814

RECRUITING NA 20 participants

rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings

West Virginia University

NCT06228235

RECRUITING NA 10 participants

A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home

Memorial Sloan Kettering Cancer Center

NCT06693700

ACTIVE NOT RECRUITING NA 153 participants

Digitally Enhanced Smoking Cessation for High Risk Smokers

Dana-Farber Cancer Institute

NCT04691297

ACTIVE NOT RECRUITING NA 23 participants

An Experimental Evaluation of Menthol-Flavored Tobacco Accessories

Virginia Polytechnic Institute and State University

NCT07092501

COMPLETED NA 1,973 participants

Interventions to Help More Low-income Smokers Quit

Washington University School of Medicine

NCT04311983

COMPLETED NA 663 participants

Tobacco/Nicotine Purchase Patterns Across SES

Virginia Polytechnic Institute and State University

NCT06795997

COMPLETED NA 658 participants

C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)

Case Comprehensive Cancer Center

NCT04358705

COMPLETED NA 194 participants

CSD210903: A Study to Determine Subject Puffing Patterns of a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in an Ambulatory Setting

RAI Services Company

NCT05307822

COMPLETED NA 171 participants

Cigarette Smoking Among Young Adults

University of Oklahoma

NCT04340947

COMPLETED NA 75 participants

CSD200907: A Study to Assess Elements of Abuse Liability for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants

RAI Services Company

NCT05114863

Phase Distribution

PhaseTrial count
Early Phase 1 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Smoking Behaviors Trial Landscape

ClinicalTrials.gov lists 22 US studies indexed under Smoking Behaviors, and 14 of those are currently open to recruitment — roughly 64% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Smoking Behaviors shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Smoking Behaviors is led by RAI Services Company with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 22 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Smoking Behaviors?

PlainTrial tracks 22 US clinical trials for Smoking Behaviors, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Smoking Behaviors?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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