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NCT07132814 · ClinicalTrials.gov registry record · NA
Abuse Liability for Five Modern Oral Nicotine Products
A NA study of Smoking and Tobacco Use, sponsored by RAI Services Company.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07132814: Recruiting NA study of Smoking and Tobacco Use, sponsored by RAI Services Company.
NCT07132814 is a NA study of Smoking and Tobacco Use that is actively recruiting participants, run by RAI Services Company. The registered enrollment target is 40 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07132814, a NA study of Smoking and Tobacco Use, is actively recruiting participants, sponsored by RAI Services Company.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a two-site, open-label, randomized, 4-way (2 arm) cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics \[PD\]) and plasma nicotine uptake (pharmacokinetics \[PK\]) during and following ad libitum use of the study investigational products (IPs) by generally healthy smokers
Primary Outcome
area under the effect curve (AUEC) for PL (VAS score-versus-time) from 5 minutes to 240 minutes after the start of IP use area under the effect curve (AUEC) for PL (VAS score-versus-time) from 5 minutes to 240 minutes after the start of IP use area under the effect curve (AUEC) for PL (VAS score-versus-time) from 5 minutes to 240 minutes after the start of IP use area under the effect curve (AUEC) for PL (VAS score-versus-time) from 5 minutes to 240 minutes after the start of IP use.
Conditions Studied
Interventions
- OTHER Product A
- OTHER Product B
- OTHER Product C
- OTHER Product D
- OTHER Product E
Study Locations (1)
Kansas
- Dr. Vince Clinical Research - Overland Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-12-15 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
What NCT07132814 shows while recruiting
NCT07132814 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (91% lower).
The record links to 4 conditions, with Smoking appearing as the primary indexed condition, and to 5 interventions - of which Product A is the first listed.
NCT07132814 reports a single indexed study location in Kansas.
Frequently Asked Questions
What is clinical trial NCT07132814 about?
NCT07132814 is a clinical study titled "Abuse Liability for Five Modern Oral Nicotine Products". This is a two-site, open-label, randomized, 4-way (2 arm) cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics \[PD\]) and plasma nicotine uptake (pharmacokinetics \[PK\]) during and following ad libitum use ...
What is the current status of trial NCT07132814?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-12-15. Estimated completion is 2026-08-31.
What conditions does trial NCT07132814 study?
This clinical trial studies the following conditions: Smoking, Tobacco Use, Tobacco Smoking, Smoking Behaviors.
What interventions are being tested in trial NCT07132814?
The interventions under investigation include: Product A (OTHER), Product B (OTHER), Product C (OTHER), Product D (OTHER), Product E (OTHER).
Who is sponsoring clinical trial NCT07132814?
This trial is sponsored by RAI Services Company, which has 42 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07132814 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07132814's enrollment target sits among peer trials
40 102nd of 123 higher than 18 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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