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NCT06077240 · ClinicalTrials.gov registry record · NA

Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction

A NA study of Smoking and Nicotine Dependence, sponsored by Yale University.

Recruiting
Registry status
NA
Development phase
256
Enrollment target
1
Study location

NCT06077240 is a NA study of Smoking and Nicotine Dependence that is actively recruiting participants, run by Yale University. The registered enrollment target is 256 participants, below the 453-participant average among 123 other Smoking trials with a reported enrollment target (43% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06077240, a NA study of Smoking and Nicotine Dependence, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
NA
Development phase
256 participants
Enrollment target
1
Study location

Study Summary

The study will recruit an anticipated 256 adults who currently smoke cigarettes and report a willingness to try switching to alternative, non-combustible products. Participants will be randomized to receive either e-cigarettes or nicotine pouches for a duration of 4 weeks and to 1 of 4 possible regulatory scenarios within products where flavor availability is either menthol and tobacco/unflavored available or tobacco/unflavored only available, and nicotine concentration is either higher (5% e-cig, 6mg pouch) or lower (2.4% e-cig, 3mg pouch). Participants will return for bi-weekly research visits (in person or remote videocall) to complete measures for study aims. Participants will complete a final follow-up at Week 6 to assess maintenance of cigarette reduction and willingness to continue using products once they are no longer provided. The investigators expect to observe which products and constituents lead to greater smoking reduction.

Interventions

  • BEHAVIORAL E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors
  • BEHAVIORAL E-cigarette with 2.4% Nicotine with Tobacco Flavor Only
  • BEHAVIORAL E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors
  • BEHAVIORAL E-cigarette with 5% Nicotine with Tobacco Flavor Only
  • BEHAVIORAL Tobacco Pouches with 3mg Nicotine with Menthol and Tobacco Flavors

Study Locations (1)

Connecticut

  • Yale University - New Haven

Trial Details

FieldValue
Enrollment Target 256 participants
Start Date 2024-08-20
Est. Completion 2028-04-01
Phase NA

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT06077240

The ClinicalTrials.gov registry entry for NCT06077240 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 256 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 453-participant average among 123 other Smoking trials with a reported enrollment target (43% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Smoking appearing as the primary indexed condition, and to 5 interventions - of which E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors is the first listed.

NCT06077240 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT06077240 about?

NCT06077240 is a clinical study titled "Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction". The study will recruit an anticipated 256 adults who currently smoke cigarettes and report a willingness to try switching to alternative, non-combustible products. Participants will be randomized to receive either e-cigarettes or nicotine pouches for a duration of 4 weeks and to 1 of 4 possible regu...

What is the current status of trial NCT06077240?

This trial is currently recruiting. It is a NA study. The enrollment target is 256 participants. The study started on 2024-08-20. Estimated completion is 2028-04-01.

What conditions does trial NCT06077240 study?

This clinical trial studies the following conditions: Smoking, Nicotine Dependence, Smoking Behaviors.

What interventions are being tested in trial NCT06077240?

The interventions under investigation include: E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors (BEHAVIORAL), E-cigarette with 2.4% Nicotine with Tobacco Flavor Only (BEHAVIORAL), E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors (BEHAVIORAL), E-cigarette with 5% Nicotine with Tobacco Flavor Only (BEHAVIORAL), Tobacco Pouches with 3mg Nicotine with Menthol and Tobacco Flavors (BEHAVIORAL).

Who is sponsoring clinical trial NCT06077240?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06077240 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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