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NCT07476144 · ClinicalTrials.gov registry record · Phase 1
Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability
A Phase 1 study of Smoking Behaviors, sponsored by JT International.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 55
- Enrollment target
- 2
- Study locations
NCT07476144: Recruiting Phase 1 study of Smoking Behaviors, sponsored by JT International.
NCT07476144 is a Phase 1 study of Smoking Behaviors that is actively recruiting participants, run by JT International. The registered enrollment target is 55 participants, below the 436-participant average among 21 other Smoking Behaviors trials with a reported enrollment target (87% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07476144, a Phase 1 study of Smoking Behaviors, is actively recruiting participants, sponsored by JT International.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 55 participants
- Enrollment target
- 2
- Study locations
Study Summary
Nicotine pharmacokinetics and subjective effects of 9 Nordic Spirit Nicotine Pouch Products in adult cigarette smokers: A controlled, randomized, cross-over study with a balanced incomplete block design.
Primary Outcome
The purpose of this study is to acquire scientific data related to nicotine PK and abuse liability NPs:Nicotine uptake levels. * Compare the abuse liability of Investigational products to UBCC, NRT and a NP comparator * Safety data in humans This study will characterize the plasma nicotine PK, subjective effects, and PD (heart rate and blood pressure) of IP's compared to UBCC, NRT, and an NP comparator. The subjective effects measures chosen for this study are standard measures to evaluate tob
Conditions Studied
Interventions
- DRUG Participants will place the pouch between their top lip and their gum for 30 minutes as per use instructions.
Study Locations (2)
Tennessee
- AMR - Knoxville
Texas
- ICON San Antonio - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2026-01-08 |
| Est. Completion | 2026-10 |
| Phase | Phase 1 |
What NCT07476144 shows while recruiting
NCT07476144 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 436-participant average among 21 other Smoking Behaviors trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Smoking Behaviors appearing as the primary indexed condition, and to 1 intervention - of which Participants will place the pouch between their top lip and their gum for 30 minutes as per use instructions. is the first listed.
NCT07476144 reports a single indexed study location in Tennessee, Texas.
Frequently Asked Questions
What is clinical trial NCT07476144 about?
NCT07476144 is a clinical study titled "Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability". Nicotine pharmacokinetics and subjective effects of 9 Nordic Spirit Nicotine Pouch Products in adult cigarette smokers: A controlled, randomized, cross-over study with a balanced incomplete block design.
What is the current status of trial NCT07476144?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 55 participants. The study started on 2026-01-08. Estimated completion is 2026-10.
What conditions does trial NCT07476144 study?
This clinical trial studies the following conditions: Smoking Behaviors.
What interventions are being tested in trial NCT07476144?
The interventions under investigation include: Participants will place the pouch between their top lip and their gum for 30 minutes as per use instructions. (DRUG).
Who is sponsoring clinical trial NCT07476144?
This trial is sponsored by JT International, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07476144 being conducted?
This trial has 2 study locations across Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking Behaviors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07476144's enrollment target sits among peer trials
55 17th of 21 higher than 5 of 21 other Smoking Behaviors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking Behaviors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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