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ClinicalTrials.gov 8 recruiting now early-phase tilt small index

Small Lymphocytic Lymphoma (SLL): early-phase trial registry

8 of 15 indexed Small Lymphocytic Lymphoma (SLL) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 8 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Small Lymphocytic Lymphoma (SLL): 15 US clinical trials tracked, 8 recruiting.

Small Lymphocytic Lymphoma (SLL) is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Nurix Therapeutics, running 3 of these trials.

Enrollment posture brief

Registry condition small-lymphocytic-lymphoma-sll

OPEN 8 | RECR 53% | LATE 0 | EARLY 13 | RANK #1140 | SPON 3

Nearest open-share peer: Beta-Thalassemia (53% recruiting · 15 trials)

Advanced Lung Non-Small Cell53.3%Small Lymphocytic Lympho (th…53%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Small Lymphocytic Lymphoma (SLL)

Small Lymphocytic Lymphoma (SLL) lists 8 open slots (53% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Small Lymphocytic Lymphoma (SLL) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Small Lymphocytic Lymphoma (SLL) is recruiting above its size-band peers.

    8 of 15 indexed trials (53.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Small Lymphocytic Lymphoma (SLL) research.

    Nurix Therapeutics accounts for 3 of 15 trials (20%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Most Small Lymphocytic Lymphoma (SLL) trials plan to enrol fewer than 100 people.

    Median target enrolment is 45 among the 15 trials that report a genuine target (sentinel values excluded). 9 of those (60%) plan for fewer than 100 participants.

  4. Small Lymphocytic Lymphoma (SLL) research is mostly interventional.

    13 interventional and 2 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 25

Open and recent trials

15 total, page 1 of 1

RECRUITING Phase 1 572 participants

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Nurix Therapeutics

NCT05131022

RECRUITING 300 participants

A Study of Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

NCT06788639

RECRUITING Phase 1 248 participants

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

Nurix Therapeutics

NCT04830137

RECRUITING Phase 2 100 participants

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

Nurix Therapeutics

NCT07221500

RECRUITING 100 participants

Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma

H. Lee Moffitt Cancer Center and Research Institute

NCT07030400

RECRUITING Phase 2 45 participants

Zanubrutinib and Venetoclax in CLL (ZANU-VEN)

Dana-Farber Cancer Institute

NCT05168930

RECRUITING Phase 2 40 participants

Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL

Massachusetts General Hospital

NCT06849713

RECRUITING Early Phase 1 30 participants

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

National Heart, Lung, and Blood Institute (NHLBI)

NCT07428707

ACTIVE NOT RECRUITING Phase 1 666 participants

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

Genmab

NCT03625037

ACTIVE NOT RECRUITING Phase 2 81 participants

Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax

Memorial Sloan Kettering Cancer Center

NCT04419519

ACTIVE NOT RECRUITING Phase 1 30 participants

A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies

Bio-Path Holdings

NCT04072458

COMPLETED Phase 1 39 participants

Study of the Efficacy and Safety of Ublituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

TG Therapeutics

NCT01647971

COMPLETED Phase 2 39 participants

Acalabrutinib and High Frequency Low Dose Subcutaneous Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma

University of Rochester

NCT03788291

COMPLETED Phase 1 24 participants

Study of AMD3100 (Plerixafor) and Rituximab in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Genzyme, a Sanofi Company

NCT00694590

COMPLETED Phase 1 18 participants

CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies

Calibr, a division of Scripps Research

NCT04450069

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 5

Named interventions

Most-linked intervention names on Small Lymphocytic Lymphoma (SLL) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

NX-5948 Drug
2 trials
Zanubrutinib Drug
2 trials
plerixafor Drug
1 trials
CLBR001 and SWI019 Combination
1 trials
L-Bcl-2 antisense oligonucleotide Drug
1 trials
Venetoclax with anti CD20 monoclonal antibody Drug
1 trials
Venetoclax monotherapy Drug
1 trials
B-Cell Lymphoma 2 Protein Inhibitor Drug
1 trials

US sites by state

Facility locations filed on Small Lymphocytic Lymphoma (SLL) trials. A trial with sites in several states counts in each.

New York 8 trials
Texas 7 trials
Tennessee 5 trials
Ohio 5 trials
Maryland 5 trials
Florida 5 trials
California 5 trials
Colorado 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Small Lymphocytic Lymphoma (SLL) page

15 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 8 Small Lymphocytic Lymphoma (SLL) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Nurix Therapeutics sponsors the most Small Lymphocytic Lymphoma (SLL) trials on record, review their full trial history before evaluating a specific study. See Nurix Therapeutics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Small Lymphocytic Lymphoma (SLL) condition card totals 15 registered trials; most-linked intervention NX-5948; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.