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ClinicalTrials.gov 12 recruiting now early-phase tilt small index

Small Cell Lung Carcinoma: early-phase trial registry

12 of 19 indexed Small Cell Lung Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 12 currently recruiting · #902 of 28,707 conditions by registered trial count

Small Cell Lung Carcinoma: 19 US clinical trials tracked, 12 recruiting.

Small Cell Lung Carcinoma is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition small-cell-lung-carcinoma

OPEN 12 | RECR 63% | LATE 2 | EARLY 15 | RANK #902 | SPON 3

Nearest open-share peer: Cervical Spinal Cord Injury (63% recruiting · 19 trials)

Small Cell Lung Carcinom (th…63%Amyotrophic Lateral Sclerosi52.6%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%
Open-enrollment share among volume-matched conditions near Small Cell Lung Carcinoma

Small Cell Lung Carcinoma lists 12 open slots (63% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Small Cell Lung Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Small Cell Lung Carcinoma is recruiting above its size-band peers.

    12 of 19 indexed trials (63.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Small Cell Lung Carcinoma research.

    Memorial Sloan Kettering Cancer Center accounts for 3 of 19 trials (15.8%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Typical Small Cell Lung Carcinoma enrolment sits around 110 participants.

    Median target enrolment is 110 among the 19 trials that report a genuine target (sentinel values excluded). 9 of those (47.4%) plan for fewer than 100 participants.

  4. Small Cell Lung Carcinoma research is mostly interventional.

    18 interventional and 1 observational studies make up this index (94.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 112Phase 23Phase 32

Open and recent trials

19 total, page 1 of 1

RECRUITING Phase 1 914 participants

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT06131840

RECRUITING 500 participants

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

Dana-Farber Cancer Institute

NCT05265429

RECRUITING Phase 1 240 participants

A Study of LY4175408 in Participants With Advanced Cancer

Eli Lilly and Company

NCT07046923

RECRUITING Phase 2 174 participants

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

Boehringer Ingelheim

NCT05882058

RECRUITING Phase 1 116 participants

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

Novartis Pharmaceuticals

NCT07006727

RECRUITING Phase 1 110 participants

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

Merck Sharp & Dohme

NCT04938817

RECRUITING NA 70 participants

A Study of Hospital-at-Home for People Receiving Tarlatamab

Memorial Sloan Kettering Cancer Center

NCT06957314

RECRUITING Phase 2 62 participants

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Memorial Sloan Kettering Cancer Center

NCT05419076

RECRUITING Phase 1 53 participants

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

Memorial Sloan Kettering Cancer Center

NCT04199741

RECRUITING Phase 1 42 participants

Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)

Washington University School of Medicine

NCT07155200

RECRUITING Phase 2 37 participants

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

University of Maryland, Baltimore

NCT05450965

RECRUITING Early Phase 1 24 participants

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

UNC Lineberger Comprehensive Cancer Center

NCT05620342

ACTIVE NOT RECRUITING Phase 3 460 participants

Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)

Merck Sharp & Dohme

NCT05224141

ACTIVE NOT RECRUITING Phase 1 269 participants

Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC)

Amgen

NCT03319940

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Cybrexa Therapeutics

NCT04902872

ACTIVE NOT RECRUITING Phase 1 31 participants

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Washington University School of Medicine

NCT05616624

COMPLETED Phase 3 1,351 participants

Trial in Extensive-Disease Small Cell Lung Cancer (ED-SCLC) Subjects Comparing Ipilimumab Plus Etoposide and Platinum Therapy to Etoposide and Platinum Therapy Alone

Bristol-Myers Squibb

NCT01450761

COMPLETED Phase 1 86 participants

A Phase 1/2a Study of ABT-263 in Subjects With Small Cell Lung Cancer (SCLC) or Other Non-Hematological Malignancies

AbbVie (prior sponsor, Abbott)

NCT00445198

COMPLETED Phase 1 28 participants

A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers

National Cancer Institute (NCI)

NCT00926640

Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 3
Phase 3 2

Named interventions

Most-linked intervention names on Small Cell Lung Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Etoposide Drug
3 trials
Cisplatin Drug
3 trials
Placebo matching Ipilimumab Biological
1 trials
ABT-263 Drug
1 trials
Adi-peg 20 Drug
1 trials
CRS Mitigation Strategies Drug
1 trials
Pembrolizumab/Vibostolimab Co-Formulation Biological
1 trials
BI 764532, dose 2 Drug
1 trials

US sites by state

Facility locations filed on Small Cell Lung Carcinoma trials. A trial with sites in several states counts in each.

Maryland 7 trials
Massachusetts 7 trials
California 7 trials
New York 6 trials
Florida 6 trials
Virginia 5 trials
Missouri 5 trials
Michigan 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Small Cell Lung Carcinoma page

19 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Small Cell Lung Carcinoma condition card totals 19 registered trials; most-linked intervention Etoposide; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.