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2026 data Public-data reference. official source

Small Cell Lung Carcinoma

Open-data reference.

19 US clinical trials · 12 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 914 participants

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT06131840

RECRUITING 500 participants

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

Dana-Farber Cancer Institute

NCT05265429

RECRUITING Phase 1 240 participants

A Study of LY4175408 in Participants With Advanced Cancer

Eli Lilly and Company

NCT07046923

RECRUITING Phase 2 174 participants

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

Boehringer Ingelheim

NCT05882058

RECRUITING Phase 1 116 participants

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

Novartis Pharmaceuticals

NCT07006727

RECRUITING Phase 1 110 participants

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)

Merck Sharp & Dohme

NCT04938817

RECRUITING NA 70 participants

A Study of Hospital-at-Home for People Receiving Tarlatamab

Memorial Sloan Kettering Cancer Center

NCT06957314

RECRUITING Phase 2 62 participants

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Memorial Sloan Kettering Cancer Center

NCT05419076

RECRUITING Phase 1 53 participants

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

Memorial Sloan Kettering Cancer Center

NCT04199741

RECRUITING Phase 1 42 participants

Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)

Washington University School of Medicine

NCT07155200

RECRUITING Phase 2 37 participants

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

University of Maryland, Baltimore

NCT05450965

RECRUITING Early Phase 1 24 participants

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

UNC Lineberger Comprehensive Cancer Center

NCT05620342

ACTIVE NOT RECRUITING Phase 3 460 participants

Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)

Merck Sharp & Dohme

NCT05224141

ACTIVE NOT RECRUITING Phase 1 269 participants

Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC)

Amgen

NCT03319940

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Cybrexa Therapeutics

NCT04902872

ACTIVE NOT RECRUITING Phase 1 31 participants

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Washington University School of Medicine

NCT05616624

COMPLETED Phase 3 1,351 participants

Trial in Extensive-Disease Small Cell Lung Cancer (ED-SCLC) Subjects Comparing Ipilimumab Plus Etoposide and Platinum Therapy to Etoposide and Platinum Therapy Alone

Bristol-Myers Squibb

NCT01450761

COMPLETED Phase 1 86 participants

A Phase 1/2a Study of ABT-263 in Subjects With Small Cell Lung Cancer (SCLC) or Other Non-Hematological Malignancies

AbbVie (prior sponsor, Abbott)

NCT00445198

COMPLETED Phase 1 28 participants

A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers

National Cancer Institute (NCI)

NCT00926640

Phase Distribution

PhaseTrial count
Early Phase 1 12
Phase 2 3
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Small Cell Lung Carcinoma Trial Landscape

ClinicalTrials.gov lists 19 US studies indexed under Small Cell Lung Carcinoma, and 12 of those are currently open to recruitment — roughly 63% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Small Cell Lung Carcinoma shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Small Cell Lung Carcinoma is led by Memorial Sloan Kettering Cancer Center with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Small Cell Lung Carcinoma?

PlainTrial tracks 19 US clinical trials for Small Cell Lung Carcinoma, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Small Cell Lung Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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