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NCT00445198 · ClinicalTrials.gov registry record · Phase 1
A Phase 1/2a Study of ABT-263 in Subjects With Small Cell Lung Cancer (SCLC) or Other Non-Hematological Malignancies
A Phase 1 study of Small-cell Lung Cancer and Small Cell Lung Carcinoma, sponsored by AbbVie (prior sponsor, Abbott).
- Completed
- Registry status
- Phase 1
- Development phase
- 86
- Enrollment target
- 18
- Study locations
NCT00445198: Completed Phase 1 study of Small-cell Lung Cancer and Small Cell Lung Carcinoma, sponsored by AbbVie (prior sponsor, Abbott).
NCT00445198 is a Phase 1 study of Small-cell Lung Cancer and Small Cell Lung Carcinoma that has completed, run by AbbVie (prior sponsor, Abbott). The registered enrollment target is 86 participants, below the 231-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (63% lower). The trial reports 18 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00445198, a Phase 1 study of Small-cell Lung Cancer and Small Cell Lung Carcinoma, has completed, sponsored by AbbVie (prior sponsor, Abbott).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 86 participants
- Enrollment target
- 18
- Study locations
Study Summary
The Phase 1 portion of the study will evaluate the pharmacokinetic profile and safety of ABT-263 with the objective of defining the dose limiting toxicity and maximum tolerated dose. (This portion of the study is complete). The Phase 2a portion of the study will evaluate ABT-263 at the defined recommended Phase 2 dose to obtain additional safety information and a preliminary assessment of efficacy.
Conditions Studied
Interventions
- DRUG ABT-263
Study Locations (18)
Other
- Site Reference ID/Investigator# 7493 - Edmonton
- Site Reference ID/Investigator# 7635 - Ottawa
- Site Reference ID/Investigator# 18541 - Leicester
- Site Reference ID/Investigator# 2622 - Manchester
Arizona
- Site Reference ID/Investigator# 13605 - Peoria
- Site Reference ID/Investigator# 5261 - Phoenix
California
- Site Reference ID/Investigator# 11942 - Los Angeles
- Site Reference ID/Investigator# 4718 - Sacramento
Maryland
- Site Reference ID/Investigator# 2625 - Baltimore
- Site Reference ID/Investigator# 12343 - Bethesda
Massachusetts
- Site Reference ID/Investigator# 11941 - Boston
- Site Reference ID/Investigator# 2626 - Boston
Colorado
- Site Reference ID/Investigator# 3755 - Aurora
Georgia
- Site Reference ID/Investigator# 8324 - Atlanta
Illinois
- Site Reference ID/Investigator# 2623 - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 86 participants |
| Start Date | 2007-04 |
| Est. Completion | 2010-12 |
| Phase | Phase 1 |
What the finished NCT00445198 record still lists
NCT00445198 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, below the 231-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (63% lower).
The record links to 2 conditions, with Small-cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which ABT-263 is the first listed.
NCT00445198 lists 18 locations in 11 states (Other, Arizona, California).
Frequently Asked Questions
What is clinical trial NCT00445198 about?
NCT00445198 is a clinical study titled "A Phase 1/2a Study of ABT-263 in Subjects With Small Cell Lung Cancer (SCLC) or Other Non-Hematological Malignancies". The Phase 1 portion of the study will evaluate the pharmacokinetic profile and safety of ABT-263 with the objective of defining the dose limiting toxicity and maximum tolerated dose. (This portion of the study is complete). The Phase 2a portion of the study will evaluate ABT-263 at the defined recom...
What is the current status of trial NCT00445198?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 86 participants. The study started on 2007-04. Estimated completion is 2010-12.
What conditions does trial NCT00445198 study?
This clinical trial studies the following conditions: Small-cell Lung Cancer, Small Cell Lung Carcinoma.
What interventions are being tested in trial NCT00445198?
The interventions under investigation include: ABT-263 (DRUG).
Who is sponsoring clinical trial NCT00445198?
This trial is sponsored by AbbVie (prior sponsor, Abbott), which has 88 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00445198 being conducted?
This trial has 18 study locations across Arizona, California, Colorado, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00445198's enrollment target sits among peer trials
86 39th of 79 higher than 41 of 79 other Small-cell Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Small-cell Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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