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ClinicalTrials.gov 12 recruiting now full pipeline

SARS CoV 2 Infection: full-pipeline trial registry

12 of 36 indexed SARS CoV 2 Infection trials are currently recruiting.

Corpus placement: #419 of 28,707 conditions by registered trial count.

36 US clinical trials · 12 currently recruiting · #419 of 28,707 conditions by registered trial count

SARS CoV 2 Infection: 36 US clinical trials tracked, 12 recruiting.

SARS CoV 2 Infection is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is BioNTech SE, running 6 of these trials.

Enrollment posture brief

Registry condition sars-cov-2-infection

OPEN 12 | RECR 33% | LATE 7 | EARLY 10 | RANK #419 | SPON 6

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Dysphagia63.9%Cognition50%Chronic Myeloid Leukemia38.9%SARS CoV 2 Infection (this)33%Coronary Disease2.8%
Open-enrollment share among volume-matched conditions near SARS CoV 2 Infection

SARS CoV 2 Infection lists 12 open slots (33% of 36 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for SARS CoV 2 Infection on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. SARS CoV 2 Infection is recruiting below its size-band peers.

    12 of 36 indexed trials (33.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates SARS CoV 2 Infection research.

    BioNTech SE accounts for 6 of 36 trials (16.7%). 24 distinct sponsors appear on at least one study for this condition label.

  3. Typical SARS CoV 2 Infection enrolment sits around 374 participants.

    Median target enrolment is 374 among the 36 trials that report a genuine target (sentinel values excluded). 7 of those (19.4%) plan for fewer than 100 participants.

  4. SARS CoV 2 Infection splits between interventional and observational designs.

    22 interventional and 14 observational studies make up this index (61.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 26Phase 36Phase 41

Open and recent trials

36 total, page 1 of 1

RECRUITING Phase 3 25,500 participants

A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age

BioNTech SE

NCT07300839

RECRUITING 10,000 participants

Influenza & COVID-19 Obstetric and Perinatal Epidemiology Study in India

Boston University

NCT06168019

RECRUITING 1,500 participants

COVID-19 Transmission and Morbidity in Malawi

Boston University

NCT05973084

RECRUITING 1,000 participants

CU-COMMITS: COVID-19 Care in Black and Latino Communities and Households. Clinical and Molecular Outcomes of SARS-CoV-2

Columbia University

NCT05467930

RECRUITING Phase 3 820 participants

Outpatient Treatment With Anti-Coronavirus Immunoglobulin

University of Minnesota

NCT04910269

RECRUITING Phase 3 550 participants

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

Wes Ely

NCT06631287

RECRUITING 350 participants

NIH RECOVER Tissue Pathology: Understanding the Long-Term Impact of COVID-19

NYU Langone Health

NCT05292274

RECRUITING NA 240 participants

Exercise in Child Health

University of California, Irvine

NCT05359991

RECRUITING Phase 1 80 participants

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

Kara Chew

NCT06810934

RECRUITING NA 60 participants

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

Vanderbilt University Medical Center

NCT05421208

RECRUITING Phase 2 50 participants

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

Vanderbilt University Medical Center

NCT07189936

RECRUITING Phase 1 24 participants

T Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients

Children's National Research Institute

NCT05141058

ACTIVE NOT RECRUITING Phase 2 30,918 participants

Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults

Medicago

NCT04636697

ACTIVE NOT RECRUITING 15,028 participants

Understanding the Long-term Impact of COVID on Children and Families

NYU Langone Health

NCT05172011

ACTIVE NOT RECRUITING 5,000 participants

Pediatric COVID Outcomes Study (PECOS)

Children's National Research Institute

NCT04830852

ACTIVE NOT RECRUITING Phase 3 760 participants

A Study to Learn About COVID-19 RNA-Based Variant-Adapted Vaccine Candidate(s) Against SARS-CoV-2 in Participants Ages 12 Through 64 Years Considered at Higher Risk of Severe COVID-19, and Participants Ages ≥65 Years

BioNTech SE

NCT07069309

ACTIVE NOT RECRUITING Phase 3 676 participants

Safety and Immunogenicity of NVX-CoV2705

Sanofi

NCT07079670

ACTIVE NOT RECRUITING Phase 4 660 participants

Impact of Reactogenicity of the 2024-2025 COVID-19 Vaccines on Health Care Workers and First Responders in the United States

Novavax

NCT06633835

ACTIVE NOT RECRUITING 500 participants

Post Acute Sequelae of COVID-19

Vanderbilt University Medical Center

NCT04964115

ACTIVE NOT RECRUITING 374 participants

ARMOR-Household: Characterizing Transmission of COVID-19 in Households of SARS-CoV-2 Index Cases

Columbia University

NCT05467917

ACTIVE NOT RECRUITING Phase 3 343 participants

A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19

BioNTech SE

NCT07222384

ACTIVE NOT RECRUITING 300 participants

Transplacental Transmission of RSV (TTRSV)

Tulane University

NCT05443607

ACTIVE NOT RECRUITING NA 256 participants

Intervention to Prevent Household and Community Spread of COVID-19 Among Latinos

San Diego State University

NCT05697068

ACTIVE NOT RECRUITING 200 participants

Cellular Senescence and COVID-19 Long-Hauler Syndrome

Mayo Clinic

NCT04903132

ACTIVE NOT RECRUITING Phase 1 51 participants

Pancoronavirus Vaccine Study in Healthy Adults

Duke University

NCT06950177

COMPLETED Phase 2 47,079 participants

Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals

BioNTech SE

NCT04368728

COMPLETED Phase 2 1,380 participants

Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants

BioNTech SE

NCT05004181

COMPLETED Phase 2 1,051 participants

A Study to Learn About New COVD-19 RNA Vaccine Candidates for New Variants in Healthy Individuals

BioNTech SE

NCT05997290

COMPLETED NA 666 participants

Culturally-Targeted COVID-19 Communication and SARS-CoV-2 Antibody Testing Evaluation and Uptake

Michigan State University

NCT04957082

COMPLETED 337 participants

COVID-19 SARS-CoV-2 RAST Study

Columbia University

NCT06452056

COMPLETED 300 participants

A Retrospective Study of COVID-19 Treatments

ProgenaBiome

NCT04949230

COMPLETED 218 participants

TekiTrust Tests to Determine the Level of SARS-COV-2/COVID-19 Neutralizing Antibodies in the Blood

MiCo BioMed Co.

NCT05338762

COMPLETED 155 participants

Index Individuals in SARS-CoV-2 Prevention Research Studies (COVID-19 Index Individuals Companion Study)

University of Washington

NCT05074719

COMPLETED NA 100 participants

Safe and Healthy Schools

University of Wisconsin, Madison

NCT05105789

COMPLETED Phase 2 28 participants

Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection

The University of Texas Health Science Center at San Antonio

NCT04818216

COMPLETED Phase 1 14 participants

Human Convalescent Plasma for High Risk Children Exposed or Infected With SARS-CoV-2 (COVID-19)

Johns Hopkins University

NCT04377672

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 6
Phase 3 6
Phase 4 1

Named interventions

Most-linked intervention names on SARS CoV 2 Infection records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Other
3 trials
BNT162b2 Biological
2 trials
Placebo Biological
2 trials
Monovalent BNT162b2 (B.1.1.529.1) Biological
1 trials
Monovalent BNT162b2 (B.1.617.2) Biological
1 trials
Monovalent BNT162b2 (B.1.1.7) Biological
1 trials
Multivalent BNT162b2 (B.1.1.7 + B.1.617.2) Biological
1 trials
Rapid Antigen Screening Test Device
1 trials

US sites by state

Facility locations filed on SARS CoV 2 Infection trials. A trial with sites in several states counts in each.

California 14 trials
New York 9 trials
Texas 7 trials
Ohio 7 trials
Arizona 7 trials
Michigan 5 trials
Illinois 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this SARS CoV 2 Infection page

36 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 12 SARS CoV 2 Infection trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • BioNTech SE sponsors the most SARS CoV 2 Infection trials on record, review their full trial history before evaluating a specific study. See BioNTech SE's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This SARS CoV 2 Infection condition card totals 36 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.