Novavax

31 total trials 27 completed

Novavax sponsors 31 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 27 completed. 10 of these trials are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is COVID-19, with 3 trials.

Trial Pipeline

31 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 4

Efficacy and Safety of NVX-CoV2705

NCT07086222

ACTIVE NOT RECRUITING Phase 4

Impact of Reactogenicity of the 2024-2025 COVID-19 Vaccines on Health Care Workers and First Responders in the United States

NCT06633835

ACTIVE NOT RECRUITING Phase 2

Study to Evaluate Safety and Immunogenicity of COVID-19 Vaccine in Children 6 Months to < 12 Years

NCT05468736

COMPLETED Phase 3

A Strain Change Study for SARS-CoV-2 rS Vaccines

NCT06409663

COMPLETED Phase 2

Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines

NCT05925127

COMPLETED Phase 2

A Study to Evaluate the Safety and Immunogenicity of an (Omicron Subvariant) COVID-19 Vaccine Booster Dose in Previously Vaccinated Participants and Unvaccinated Participants.

NCT05975060

COMPLETED Phase 3

Phase 3 Adolescent Study for SARS-CoV-2 rS Variant Vaccines

NCT05973006

COMPLETED Phase 3

Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines

NCT05875701

COMPLETED Phase 3

Study to Compare the Immunogenicity and Safety of 3 Lots of NVX-CoV2373 in Adults

NCT05463068

COMPLETED Phase 3

A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2

NCT04611802

COMPLETED Phase 1

Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS Nanoparticle Vaccine With/Without Matrix-M Adjuvant

NCT04368988

COMPLETED Phase 3

Phase 3 Pivotal Trial of NanoFlu™ in Older Adults

NCT04120194

TERMINATED Phase 2

Phase 2 Dose and Formulation Confirmation of Quad-NIV in Older Adults

NCT03658629

COMPLETED Phase 1

Evaluation of the Safety and Immunogenicity of a Recombinant Trivalent Nanoparticle Influenza Vaccine With Matrix M-1 Adjuvant (NanoFlu)

NCT03293498

COMPLETED Phase 3

A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization

NCT02624947

COMPLETED Phase 3

A Study to Evaluate the Efficacy of an RSV F Vaccine in Older Adults

NCT02608502

COMPLETED Phase 2

Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.

NCT02593071

COMPLETED Phase 2

Quadrivalent Influenza VLP Vaccine Dose Ranging Study in Young Adults

NCT02307851

COMPLETED Phase 2

Placebo- Controlled Study to Evaluate the Safety and Immunogenicity of the RSV-F Vaccine in Elderly Adults

NCT02266628

COMPLETED Phase 2

RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.

NCT02247726

COMPLETED Phase 1

A(H7N9) VLP Antigen Dose-Ranging Study With Matrix-M1™ Adjuvant

NCT02078674

COMPLETED Phase 2

RSV F Dose-Ranging Study in Women

NCT01960686

COMPLETED Phase 2

RSV-F Vaccine Dose Ranging Study in Young Women

NCT01704365

COMPLETED Phase 1

RSV-F Vaccine and Influenza Vaccine Co-Administration Study in the Elderly

NCT01709019

COMPLETED Phase 1

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 2

NCT01596725

COMPLETED Phase 1

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1

NCT01594320

COMPLETED Phase 1

Safety Study of Respiratory Syncytial Virus (RSV)-Fusion (F) Protein Particle Vaccine

NCT01290419

COMPLETED Phase 2

Evaluate the Safety and Immunogenicity of a Seasonal Influenza Virus-Like Particle (VLP) Vaccine in Older Adults

NCT01014806

COMPLETED Phase 2

Trial to Evaluate Safety and Immunogenicity of Trivalent Seasonal Influenza Virus-Like Particle (VLP) Vaccine (Recombinant)

NCT00903552

COMPLETED Phase 2

Evaluate the Safety and Immunogenicity of a Seasonal Influenza VLP Vaccine (Recombinant) in Healthy Adults

NCT00754455

COMPLETED Phase 1

Safety, Reactogenicity and Immunogenicity of an H5N1 VLP

NCT00519389

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 13
Phase 3 8
Phase 4 2

What the Pipeline for Novavax Shows

According to the ClinicalTrials.gov registry, Novavax is linked to 31 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 27 are already marked complete, representing roughly 87% of the total.

The phase mix for Novavax reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 21 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Novavax is COVID-19 with 3 linked trials, and 7 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.