Novavax

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, Novavax sits in the top decile of US sponsors by registered trial count (#526 of 15,742 sponsors by registered trial count).

31 total trials none currently recruiting 27 completed early-phase tilt top decile by trial count

Novavax: 31 sponsored US clinical trials, none currently recruiting.

Novavax sponsors 31 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 27 completed. 10 of these trials are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is COVID-19, with 4 trials.

Top-decile sponsor footprint

Novavax ranks in the top decile of sponsors by registered trial count (#526 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

B 81/100

27 of 28 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (96.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

31 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 4

Efficacy and Safety of NVX-CoV2705

NCT07086222

ACTIVE NOT RECRUITING Phase 4

Impact of Reactogenicity of the 2024-2025 COVID-19 Vaccines on Health Care Workers and First Responders in the United States

NCT06633835

ACTIVE NOT RECRUITING Phase 2

Study to Evaluate Safety and Immunogenicity of COVID-19 Vaccine in Children 6 Months to < 12 Years

NCT05468736

COMPLETED Phase 3

A Strain Change Study for SARS-CoV-2 rS Vaccines

NCT06409663

COMPLETED Phase 2

Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines

NCT05925127

COMPLETED Phase 2

A Study to Evaluate the Safety and Immunogenicity of an (Omicron Subvariant) COVID-19 Vaccine Booster Dose in Previously Vaccinated Participants and Unvaccinated Participants.

NCT05975060

COMPLETED Phase 3

Phase 3 Adolescent Study for SARS-CoV-2 rS Variant Vaccines

NCT05973006

COMPLETED Phase 3

Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines

NCT05875701

COMPLETED Phase 3

Study to Compare the Immunogenicity and Safety of 3 Lots of NVX-CoV2373 in Adults

NCT05463068

COMPLETED Phase 3

A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2

NCT04611802

COMPLETED Phase 1

Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS Nanoparticle Vaccine With/Without Matrix-M Adjuvant

NCT04368988

COMPLETED Phase 3

Phase 3 Pivotal Trial of NanoFlu™ in Older Adults

NCT04120194

TERMINATED Phase 2

Phase 2 Dose and Formulation Confirmation of Quad-NIV in Older Adults

NCT03658629

COMPLETED Phase 1

Evaluation of the Safety and Immunogenicity of a Recombinant Trivalent Nanoparticle Influenza Vaccine With Matrix M-1 Adjuvant (NanoFlu)

NCT03293498

COMPLETED Phase 3

A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization

NCT02624947

COMPLETED Phase 3

A Study to Evaluate the Efficacy of an RSV F Vaccine in Older Adults

NCT02608502

COMPLETED Phase 2

Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.

NCT02593071

COMPLETED Phase 2

Quadrivalent Influenza VLP Vaccine Dose Ranging Study in Young Adults

NCT02307851

COMPLETED Phase 2

Placebo- Controlled Study to Evaluate the Safety and Immunogenicity of the RSV-F Vaccine in Elderly Adults

NCT02266628

COMPLETED Phase 2

RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.

NCT02247726

COMPLETED Phase 1

A(H7N9) VLP Antigen Dose-Ranging Study With Matrix-M1™ Adjuvant

NCT02078674

COMPLETED Phase 2

RSV F Dose-Ranging Study in Women

NCT01960686

COMPLETED Phase 2

RSV-F Vaccine Dose Ranging Study in Young Women

NCT01704365

COMPLETED Phase 1

RSV-F Vaccine and Influenza Vaccine Co-Administration Study in the Elderly

NCT01709019

COMPLETED Phase 1

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 2

NCT01596725

COMPLETED Phase 1

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1

NCT01594320

COMPLETED Phase 1

Safety Study of Respiratory Syncytial Virus (RSV)-Fusion (F) Protein Particle Vaccine

NCT01290419

COMPLETED Phase 2

Evaluate the Safety and Immunogenicity of a Seasonal Influenza Virus-Like Particle (VLP) Vaccine in Older Adults

NCT01014806

COMPLETED Phase 2

Trial to Evaluate Safety and Immunogenicity of Trivalent Seasonal Influenza Virus-Like Particle (VLP) Vaccine (Recombinant)

NCT00903552

COMPLETED Phase 2

Evaluate the Safety and Immunogenicity of a Seasonal Influenza VLP Vaccine (Recombinant) in Healthy Adults

NCT00754455

COMPLETED Phase 1

Safety, Reactogenicity and Immunogenicity of an H5N1 VLP

NCT00519389

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 13
Phase 3 8
Phase 4 2

How the Novavax early-phase archive is shaped

31 indexed studies, none listed as recruiting (0% open); 27 completed (87%).

Phase mix: 10 late (III/IV) vs 21 early (I/II) (early-phase heavy).

Top condition: COVID-19 (4 trials), 6 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Novavax: archived-pipeline peers nationwide

Peers matched on 31 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Novavax sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 010203040 0%5%10%15% Total trials Recruiting share NovavaxChildren's Hospitals and Clinics of MinnesotaCook Group IncorporatedCytokineticsHalozyme Therapeutics10xBio22nd Century Group23andMe3-C Institute for Social Development
Novavax sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Novavax sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 31 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Novavax page

31 registered trials is a research-attention snapshot, not an endorsement of Novavax or any single study.

  • None of Novavax's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • COVID-19 is the condition Novavax studies most, compare against other sponsors active in the same condition before evaluating a specific study. See COVID-19 trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Novavax pipeline card: 31 registered trials from official public datasets.Report a data error.