Novavax
Novavax sponsors 31 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 27 completed. 10 of these trials are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is COVID-19, with 3 trials.
Trial Pipeline
31 total, page 1 of 1
Efficacy and Safety of NVX-CoV2705
NCT07086222
Impact of Reactogenicity of the 2024-2025 COVID-19 Vaccines on Health Care Workers and First Responders in the United States
NCT06633835
Study to Evaluate Safety and Immunogenicity of COVID-19 Vaccine in Children 6 Months to < 12 Years
NCT05468736
A Strain Change Study for SARS-CoV-2 rS Vaccines
NCT06409663
Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines
NCT05925127
A Study to Evaluate the Safety and Immunogenicity of an (Omicron Subvariant) COVID-19 Vaccine Booster Dose in Previously Vaccinated Participants and Unvaccinated Participants.
NCT05975060
Phase 3 Adolescent Study for SARS-CoV-2 rS Variant Vaccines
NCT05973006
Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines
NCT05875701
Study to Compare the Immunogenicity and Safety of 3 Lots of NVX-CoV2373 in Adults
NCT05463068
A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2
NCT04611802
Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS Nanoparticle Vaccine With/Without Matrix-M Adjuvant
NCT04368988
Phase 3 Pivotal Trial of NanoFlu™ in Older Adults
NCT04120194
Phase 2 Dose and Formulation Confirmation of Quad-NIV in Older Adults
NCT03658629
Evaluation of the Safety and Immunogenicity of a Recombinant Trivalent Nanoparticle Influenza Vaccine With Matrix M-1 Adjuvant (NanoFlu)
NCT03293498
A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization
NCT02624947
A Study to Evaluate the Efficacy of an RSV F Vaccine in Older Adults
NCT02608502
Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.
NCT02593071
Quadrivalent Influenza VLP Vaccine Dose Ranging Study in Young Adults
NCT02307851
Placebo- Controlled Study to Evaluate the Safety and Immunogenicity of the RSV-F Vaccine in Elderly Adults
NCT02266628
RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.
NCT02247726
A(H7N9) VLP Antigen Dose-Ranging Study With Matrix-M1™ Adjuvant
NCT02078674
RSV F Dose-Ranging Study in Women
NCT01960686
RSV-F Vaccine Dose Ranging Study in Young Women
NCT01704365
RSV-F Vaccine and Influenza Vaccine Co-Administration Study in the Elderly
NCT01709019
A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 2
NCT01596725
A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1
NCT01594320
Safety Study of Respiratory Syncytial Virus (RSV)-Fusion (F) Protein Particle Vaccine
NCT01290419
Evaluate the Safety and Immunogenicity of a Seasonal Influenza Virus-Like Particle (VLP) Vaccine in Older Adults
NCT01014806
Trial to Evaluate Safety and Immunogenicity of Trivalent Seasonal Influenza Virus-Like Particle (VLP) Vaccine (Recombinant)
NCT00903552
Evaluate the Safety and Immunogenicity of a Seasonal Influenza VLP Vaccine (Recombinant) in Healthy Adults
NCT00754455
Safety, Reactogenicity and Immunogenicity of an H5N1 VLP
NCT00519389
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 2 | 13 |
| Phase 3 | 8 |
| Phase 4 | 2 |
What the Pipeline for Novavax Shows
According to the ClinicalTrials.gov registry, Novavax is linked to 31 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 27 are already marked complete, representing roughly 87% of the total.
The phase mix for Novavax reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 21 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Novavax is COVID-19 with 3 linked trials, and 7 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.