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NCT05421208 · ClinicalTrials.gov registry record · NA

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

A NA study of Long COVID and SARS CoV 2 Infection, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
NA
Development phase
60
Enrollment target
1
Study location

NCT05421208 is a NA study of Long COVID and SARS CoV 2 Infection that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 60 participants, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05421208, a NA study of Long COVID and SARS CoV 2 Infection, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
NA
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists beyond the 3-month convalescence period after COVID-19 infections. This syndrome affects mostly women (\~80%), present with chronic tachycardia and Orthostatic intolerance symptoms without any identifiable cause. In addition, non-specific symptoms such as fatigue, headache, and "brain fog", commonly described in POTS patients are also present in this novel condition, recently named post-COVID-19 tachycardia syndrome, POTS variant. Reduced Vagal activity and unresolved inflammation is post-COVID-19 POTS is hypothesized as the cause of Long COVID

Conditions Studied

Long COVID SARS CoV 2 Infection Post-Acute COVID-19 Syndrome Postural Tachycardia Syndrome (POTS)

Interventions

  • DIAGNOSTIC_TEST Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls
  • DIAGNOSTIC_TEST Levels of inflammatory cytokine ( IL-6) in controls
  • DIAGNOSTIC_TEST Effect on inflammation after chronic PNS stimulation

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2022-06-01
Est. Completion 2027-06-30
Phase NA

Sponsor

Vanderbilt University Medical Center

677 total trials

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What the Registry Record Tells You About NCT05421208

The ClinicalTrials.gov registry entry for NCT05421208 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (97% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Long COVID appearing as the primary indexed condition, and to 3 interventions - of which Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls is the first listed.

NCT05421208 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT05421208 about?

NCT05421208 is a clinical study titled "Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome". The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists beyond the 3-month convalescence period after COVID-19 infections. This syndrome affects mostly women (\~80%), present with chronic tachycardia and Orthostatic intolerance symptoms without any identifiable cau...

What is the current status of trial NCT05421208?

This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2022-06-01. Estimated completion is 2027-06-30.

What conditions does trial NCT05421208 study?

This clinical trial studies the following conditions: Long COVID, SARS CoV 2 Infection, Post-Acute COVID-19 Syndrome, Postural Tachycardia Syndrome (POTS).

What interventions are being tested in trial NCT05421208?

The interventions under investigation include: Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls (DIAGNOSTIC_TEST), Levels of inflammatory cytokine ( IL-6) in controls (DIAGNOSTIC_TEST), Effect on inflammation after chronic PNS stimulation (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05421208?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05421208 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.