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ClinicalTrials.gov 3 recruiting now early-phase tilt

Renal Insufficiency: early-phase trial registry

3 of 23 indexed Renal Insufficiency trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #724 of 28,707 conditions by registered trial count.

23 US clinical trials · 3 currently recruiting · #724 of 28,707 conditions by registered trial count

Renal Insufficiency: 23 US clinical trials tracked, 3 recruiting.

Renal Insufficiency is the subject of 23 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 6 of these trials.

Enrollment posture brief

Registry condition renal-insufficiency

OPEN 3 | RECR 13% | LATE 2 | EARLY 15 | RANK #724 | SPON 6

Nearest open-share peer: Chest Pain (13% recruiting · 23 trials)

Breast Cancer Stage II47.8%Advanced Non-Small-Cell Lung39.1%Anxiety Disorder30.4%Barrett's Esophagus26.1%Renal Insufficiency (this)13%
Open-enrollment share among volume-matched conditions near Renal Insufficiency

Renal Insufficiency lists 3 open slots (13% of 23 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Renal Insufficiency on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Renal Insufficiency is recruiting below its size-band peers.

    3 of 23 indexed trials (13%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Renal Insufficiency research.

    Eli Lilly and Company accounts for 6 of 23 trials (26.1%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Most Renal Insufficiency trials plan to enrol fewer than 100 people.

    Median target enrolment is 32 among the 23 trials that report a genuine target (sentinel values excluded). 18 of those (78.3%) plan for fewer than 100 participants.

  4. Renal Insufficiency research is mostly interventional.

    19 interventional and 4 observational studies make up this index (82.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 114Phase 21Phase 31Phase 41

Open and recent trials

23 total, page 1 of 1

RECRUITING NA 600 participants

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

VenoStent

NCT06001827

RECRUITING Phase 1 32 participants

A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function

Eli Lilly and Company

NCT07137689

RECRUITING Phase 1 28 participants

A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function

Eli Lilly and Company

NCT07426380

ACTIVE NOT RECRUITING Phase 1 32 participants

A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment

Eli Lilly and Company

NCT07165015

COMPLETED 405 participants

Evaluation of the Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Without Exposure to Gadolinium Based Contrast Agents (GBCA)

Bracco Diagnostics

NCT00773409

COMPLETED 366 participants

Evaluation of the Risk of NSF Following MultiHance Injection in Patients With Chronic Kidney Disease

Bracco Diagnostics

NCT00600951

COMPLETED Phase 3 200 participants

Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D

Denver Nephrologists, P.C.

NCT02492620

COMPLETED Phase 4 114 participants

Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency

Loyola University

NCT00911625

COMPLETED Phase 1 48 participants

A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment

Celgene

NCT03097016

COMPLETED Phase 1 47 participants

A Study of LY3473329 in Participants With Impaired and Normal Renal Function

Eli Lilly and Company

NCT05778864

COMPLETED NA 46 participants

Remote Ischemic Preconditioning for Renal Protection in TAVI

Henry Ford Health System

NCT03347032

COMPLETED Phase 1 45 participants

Pharmacokinetics and Safety of Fevipiprant in Patients With Renal Impairment Compared to Matched Healthy Subjects

Novartis Pharmaceuticals

NCT03087942

COMPLETED Phase 1 37 participants

A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal Function

Eli Lilly and Company

NCT05469100

COMPLETED 32 participants

The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™

FAST BioMedical

NCT03095391

COMPLETED Phase 1 29 participants

A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney Function

GlaxoSmithKline

NCT00501462

COMPLETED Phase 1 29 participants

A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function

Janssen Research & Development

NCT01309438

COMPLETED Phase 1 26 participants

A Study of LY3819469 in Participants With Impaired and Normal Renal Function

Eli Lilly and Company

NCT05841277

COMPLETED Phase 1 25 participants

Pharmacokinetic Evaluation of Tirofiban Using a Single High-Dose Bolus In Subjects With Varying Degrees of Renal Function

Medicure

NCT01766154

COMPLETED Phase 1 23 participants

Study Assessing PK and Safety of MGTA-145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal Impairment

Ensoma

NCT04154670

COMPLETED Phase 2 20 participants

A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency

BioCryst Pharmaceuticals

NCT01407874

COMPLETED 18 participants

Pharmacokinetics of Antiepileptics in Patients on CRRT

University of Maryland, Baltimore

NCT03632915

COMPLETED Phase 1 16 participants

A Pharmacokinetic Study of Abiraterone Acetate in Male Participants With Impaired Renal Function Compared to Individuals With Normal Renal Function

Cougar Biotechnology

NCT01715259

COMPLETED Phase 1 9 participants

"Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction"

Duke University

NCT01121770

Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 1
Phase 3 1
Phase 4 1

Top Sponsors

Named interventions

Most-linked intervention names on Renal Insufficiency records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Iohexol Device
1 trials
VFI Device
1 trials
Tirofiban Drug
1 trials
Erythromycin (mild and moderate renal function) Drug
1 trials
Erythromycin (normal renal function) Drug
1 trials
Rivaroxaban (mild and moderate renal impairment) Drug
1 trials
Rivaroxaban (normal renal function) Drug
1 trials
LY3473329 Drug
1 trials

US sites by state

Facility locations filed on Renal Insufficiency trials. A trial with sites in several states counts in each.

Florida 14 trials
Tennessee 5 trials
Minnesota 5 trials
Texas 3 trials
California 3 trials
New Jersey 2 trials
North Carolina 2 trials
Indiana 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Renal Insufficiency page

23 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Renal Insufficiency condition card totals 23 registered trials; most-linked intervention Iohexol; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.