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2026 data Public-data reference. official source

Renal Insufficiency

Open-data reference.

23 US clinical trials · 3 currently recruiting

Active & Recent Trials

RECRUITING NA 600 participants

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

VenoStent

NCT06001827

RECRUITING Phase 1 32 participants

A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function

Eli Lilly and Company

NCT07137689

RECRUITING Phase 1 28 participants

A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function

Eli Lilly and Company

NCT07426380

ACTIVE NOT RECRUITING Phase 1 32 participants

A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment

Eli Lilly and Company

NCT07165015

COMPLETED 405 participants

Evaluation of the Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Without Exposure to Gadolinium Based Contrast Agents (GBCA)

Bracco Diagnostics

NCT00773409

COMPLETED 366 participants

Evaluation of the Risk of NSF Following MultiHance Injection in Patients With Chronic Kidney Disease

Bracco Diagnostics

NCT00600951

COMPLETED Phase 3 200 participants

Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D

Denver Nephrologists, P.C.

NCT02492620

COMPLETED Phase 4 114 participants

Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency

Loyola University

NCT00911625

COMPLETED Phase 1 48 participants

A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment

Celgene

NCT03097016

COMPLETED Phase 1 47 participants

A Study of LY3473329 in Participants With Impaired and Normal Renal Function

Eli Lilly and Company

NCT05778864

COMPLETED NA 46 participants

Remote Ischemic Preconditioning for Renal Protection in TAVI

Henry Ford Health System

NCT03347032

COMPLETED Phase 1 45 participants

Pharmacokinetics and Safety of Fevipiprant in Patients With Renal Impairment Compared to Matched Healthy Subjects

Novartis Pharmaceuticals

NCT03087942

COMPLETED Phase 1 37 participants

A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal Function

Eli Lilly and Company

NCT05469100

COMPLETED 32 participants

The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™

FAST BioMedical

NCT03095391

COMPLETED Phase 1 29 participants

A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney Function

GlaxoSmithKline

NCT00501462

COMPLETED Phase 1 29 participants

A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function

Janssen Research & Development

NCT01309438

COMPLETED Phase 1 26 participants

A Study of LY3819469 in Participants With Impaired and Normal Renal Function

Eli Lilly and Company

NCT05841277

COMPLETED Phase 1 25 participants

Pharmacokinetic Evaluation of Tirofiban Using a Single High-Dose Bolus In Subjects With Varying Degrees of Renal Function

Medicure

NCT01766154

COMPLETED Phase 1 23 participants

Study Assessing PK and Safety of MGTA-145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal Impairment

Ensoma

NCT04154670

COMPLETED Phase 2 20 participants

A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency

BioCryst Pharmaceuticals

NCT01407874

COMPLETED 18 participants

Pharmacokinetics of Antiepileptics in Patients on CRRT

University of Maryland, Baltimore

NCT03632915

COMPLETED Phase 1 16 participants

A Pharmacokinetic Study of Abiraterone Acetate in Male Participants With Impaired Renal Function Compared to Individuals With Normal Renal Function

Cougar Biotechnology

NCT01715259

COMPLETED Phase 1 9 participants

"Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction"

Duke University

NCT01121770

Phase Distribution

PhaseTrial count
Early Phase 1 14
Phase 2 1
Phase 3 1
Phase 4 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Renal Insufficiency Trial Landscape

ClinicalTrials.gov lists 23 US studies indexed under Renal Insufficiency, and 3 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Renal Insufficiency shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Renal Insufficiency is led by Eli Lilly and Company with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Renal Insufficiency?

PlainTrial tracks 23 US clinical trials for Renal Insufficiency, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Renal Insufficiency?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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