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Renal Insufficiency
Open-data reference.
23 US clinical trials · 3 currently recruiting
Active & Recent Trials
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
VenoStent
NCT06001827
A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function
Eli Lilly and Company
NCT07137689
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
Eli Lilly and Company
NCT07426380
A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment
Eli Lilly and Company
NCT07165015
Evaluation of the Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Chronic Kidney Disease Without Exposure to Gadolinium Based Contrast Agents (GBCA)
Bracco Diagnostics
NCT00773409
Evaluation of the Risk of NSF Following MultiHance Injection in Patients With Chronic Kidney Disease
Bracco Diagnostics
NCT00600951
Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D
Denver Nephrologists, P.C.
NCT02492620
Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency
Loyola University
NCT00911625
A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment
Celgene
NCT03097016
A Study of LY3473329 in Participants With Impaired and Normal Renal Function
Eli Lilly and Company
NCT05778864
Remote Ischemic Preconditioning for Renal Protection in TAVI
Henry Ford Health System
NCT03347032
Pharmacokinetics and Safety of Fevipiprant in Patients With Renal Impairment Compared to Matched Healthy Subjects
Novartis Pharmaceuticals
NCT03087942
A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal Function
Eli Lilly and Company
NCT05469100
The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™
FAST BioMedical
NCT03095391
A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney Function
GlaxoSmithKline
NCT00501462
A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function
Janssen Research & Development
NCT01309438
A Study of LY3819469 in Participants With Impaired and Normal Renal Function
Eli Lilly and Company
NCT05841277
Pharmacokinetic Evaluation of Tirofiban Using a Single High-Dose Bolus In Subjects With Varying Degrees of Renal Function
Medicure
NCT01766154
Study Assessing PK and Safety of MGTA-145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal Impairment
Ensoma
NCT04154670
A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency
BioCryst Pharmaceuticals
NCT01407874
Pharmacokinetics of Antiepileptics in Patients on CRRT
University of Maryland, Baltimore
NCT03632915
A Pharmacokinetic Study of Abiraterone Acetate in Male Participants With Impaired Renal Function Compared to Individuals With Normal Renal Function
Cougar Biotechnology
NCT01715259
"Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction"
Duke University
NCT01121770
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 14 |
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Renal Insufficiency Trial Landscape
ClinicalTrials.gov lists 23 US studies indexed under Renal Insufficiency, and 3 of those are currently open to recruitment — roughly 13% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Renal Insufficiency shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Renal Insufficiency is led by Eli Lilly and Company with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Renal Insufficiency?
PlainTrial tracks 23 US clinical trials for Renal Insufficiency, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Renal Insufficiency?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.