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NCT05469100 · ClinicalTrials.gov registry record · Phase 1

A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal Function

A Phase 1 study of Healthy and Renal Insufficiency, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
37
Enrollment target
6
Study locations

NCT05469100 is a Phase 1 study of Healthy and Renal Insufficiency that has completed, run by Eli Lilly and Company. The registered enrollment target is 37 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The trial reports 6 study locations across 2 states.

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The verdict

NCT05469100, a Phase 1 study of Healthy and Renal Insufficiency, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
37 participants
Enrollment target
6
Study locations

Study Summary

The main purpose of this study is to assess the amount of study drug that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment compared to healthy participants. The study will last up to 9 days, excluding screening.

Interventions

  • DRUG Selpercatinib

Study Locations (6)

California

  • Anaheim Regional Center - Anaheim
  • Stanford Health Care, Valley Care Program - Pleasanton
  • Orange County Research Center - Tustin

Florida

  • Riverside Clinical Research - Edgewater
  • Clinical Pharmacology of Miami - Miami
  • Orlando Clinical Research Center - Orlando

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2018-12-19
Est. Completion 2019-08-07
Phase Phase 1

Sponsor

Eli Lilly and Company

1,341 total trials

What the Registry Record Tells You About NCT05469100

The ClinicalTrials.gov registry entry for NCT05469100 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Selpercatinib is the first listed.

NCT05469100 reports 6 study locations spanning 2 distinct geographic areas - top geographies include California, Florida.

Frequently Asked Questions

What is clinical trial NCT05469100 about?

NCT05469100 is a clinical study titled "A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal Function". The main purpose of this study is to assess the amount of study drug that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment compared to healthy participants. The study will last up to 9 days, excluding screening.

What is the current status of trial NCT05469100?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2018-12-19. Estimated completion is 2019-08-07.

What conditions does trial NCT05469100 study?

This clinical trial studies the following conditions: Healthy, Renal Insufficiency.

What interventions are being tested in trial NCT05469100?

The interventions under investigation include: Selpercatinib (DRUG).

Who is sponsoring clinical trial NCT05469100?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05469100 being conducted?

This trial has 6 study locations across California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.