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2026 data Public-data reference. official source

Relapsed/Refractory Multiple Myeloma

Open-data reference.

10 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 246 participants

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

BeOne Medicines

NCT04973605

RECRUITING Phase 1 200 participants

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)

Ichnos Sciences

NCT05862012

RECRUITING Phase 2 100 participants

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

C4 Therapeutics

NCT07284758

RECRUITING Phase 1 50 participants

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

Caribou Biosciences

NCT05722418

ACTIVE NOT RECRUITING Phase 1 283 participants

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused Etentamig (ABBV-383) in Combination With Anti-Cancer Regimens for the Treatment of Adult Participants With Relapsed/Refractory Multiple Myeloma

AbbVie

NCT05259839

ACTIVE NOT RECRUITING Phase 1 132 participants

Safety and Efficacy of ALLO-715 BCMA Allogenic CAR T Cells in in Adults With Relapsed or Refractory Multiple Myeloma (UNIVERSAL)

Allogene Therapeutics

NCT04093596

ACTIVE NOT RECRUITING Phase 1 34 participants

A Study to Assess the Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma Receiving Oral ABBV-453 Tablets

AbbVie

NCT05308654

ACTIVE NOT RECRUITING Phase 2 30 participants

Cevostamab Following CAR T Cell Therapy for RRMM

University of Pennsylvania

NCT05801939

COMPLETED Phase 3 291 participants

A Study Evaluating Venetoclax (ABT-199) in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy

AbbVie

NCT02755597

COMPLETED Phase 3 255 participants

Aplidin - Dexamethasone in Relapsed/Refractory Myeloma

PharmaMar

NCT01102426

Phase Distribution

PhaseTrial count
Early Phase 1 6
Phase 2 2
Phase 3 2

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Relapsed/Refractory Multiple Myeloma Trial Landscape

ClinicalTrials.gov lists 10 US studies indexed under Relapsed/Refractory Multiple Myeloma, and 4 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Relapsed/Refractory Multiple Myeloma shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Relapsed/Refractory Multiple Myeloma is led by AbbVie with 3 indexed trials, alongside 7 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Relapsed/Refractory Multiple Myeloma?

PlainTrial tracks 10 US clinical trials for Relapsed/Refractory Multiple Myeloma, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Relapsed/Refractory Multiple Myeloma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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