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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Recurrent Medulloblastoma: early-phase trial registry

3 of 13 indexed Recurrent Medulloblastoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 3 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Recurrent Medulloblastoma: 13 US clinical trials tracked, 3 recruiting.

Recurrent Medulloblastoma is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.

Enrollment posture brief

Registry condition recurrent-medulloblastoma

OPEN 3 | RECR 23% | LATE 0 | EARLY 13 | RANK #1315 | SPON 6

Nearest open-share peer: Endometrial Serous Adenocarcinoma (23% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Recurrent Medulloblastom (th…23%
Open-enrollment share among volume-matched conditions near Recurrent Medulloblastoma

Recurrent Medulloblastoma lists 3 open slots (23% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Medulloblastoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Medulloblastoma is recruiting below its size-band peers.

    3 of 13 indexed trials (23.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Medulloblastoma research.

    National Cancer Institute (NCI) accounts for 6 of 13 trials (46.2%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Medulloblastoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 30 among the 13 trials that report a genuine target (sentinel values excluded). 12 of those (92.3%) plan for fewer than 100 participants.

  4. Recurrent Medulloblastoma research is mostly interventional.

    13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 26

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 2 120 participants

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Nationwide Children's Hospital

NCT05096481

RECRUITING Phase 1 65 participants

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Nationwide Children's Hospital

NCT05278208

RECRUITING Phase 1 18 participants

GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults

Stanford University

NCT07087002

ACTIVE NOT RECRUITING Phase 1 71 participants

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

National Cancer Institute (NCI)

NCT02359565

ACTIVE NOT RECRUITING Phase 2 62 participants

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

Pediatric Brain Tumor Consortium

NCT04743661

ACTIVE NOT RECRUITING Phase 1 41 participants

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

National Cancer Institute (NCI)

NCT03598244

ACTIVE NOT RECRUITING Early Phase 1 30 participants

Fimepinostat in Treating Brain Tumors in Children and Young Adults

Sabine Mueller, MD, PhD

NCT03893487

ACTIVE NOT RECRUITING Phase 1 30 participants

PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma

Daniel Landi

NCT03299309

ACTIVE NOT RECRUITING Phase 2 20 participants

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03698994

ACTIVE NOT RECRUITING Phase 2 13 participants

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03213652

ACTIVE NOT RECRUITING Phase 2 3 participants

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT04195555

COMPLETED Phase 2 23 participants

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

NCT03526250

COMPLETED Phase 1 22 participants

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Pediatric Brain Tumor Consortium

NCT03387020

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 6

Named interventions

Most-linked intervention names on Recurrent Medulloblastoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
3 trials
Pharmacological Study Other
2 trials
Temozolomide Drug
2 trials
Laboratory Biomarker Analysis Other
2 trials
Liothyronine Drug
1 trials
Omburtamab I-131 Drug
1 trials
Dynamic Contrast-enhanced MR Perfusion Procedure
1 trials
Diffusion Tensor Imaging Procedure
1 trials

US sites by state

Facility locations filed on Recurrent Medulloblastoma trials. A trial with sites in several states counts in each.

California 10 trials
Colorado 8 trials
Ohio 7 trials
Pennsylvania 6 trials
Texas 5 trials
Tennessee 4 trials
New York 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Medulloblastoma page

13 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Medulloblastoma condition card totals 13 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.