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ClinicalTrials.gov 1 recruiting now official registry

Recurrent Adult Acute Lymphoblastic Leukemia clinical trials

1 of 9 indexed Recurrent Adult Acute Lymphoblastic Leukemia trials are currently recruiting.

9 US clinical trials · 1 currently recruiting

Recurrent Adult Acute Lymphoblastic Leukemia is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 4 of these trials.

The research picture

Recurrent Adult Acute Lymphoblastic Leukemia has 9 registered US clinical trials, 1 of them open to new participants right now, about 11% of the total.

1
recruiting participants now
11%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
4
top sponsor: National Cancer Institute (NCI)
Phase 15Phase 24

Active & Recent Trials

9 total, page 1 of 1

RECRUITING Phase 1 30 participants

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

University of Chicago

NCT02333162

ACTIVE NOT RECRUITING Phase 2 108 participants

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

City of Hope Medical Center

NCT02094794

ACTIVE NOT RECRUITING Phase 2 97 participants

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT00792948

ACTIVE NOT RECRUITING Phase 1 33 participants

Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults w/ Recurrent or Refractory B Cell Malignancies

Stanford University

NCT03241940

COMPLETED Phase 1 124 participants

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

Mayo Clinic

NCT00918333

COMPLETED Phase 2 74 participants

CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase

National Cancer Institute (NCI)

NCT00084916

COMPLETED Phase 1 50 participants

S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia

SWOG Cancer Research Network

NCT01925131

COMPLETED Phase 1 27 participants

Entinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia

National Cancer Institute (NCI)

NCT01132573

COMPLETED Phase 2 16 participants

Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT02484430

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Adult Acute Lymphoblastic Leukemia Trial Landscape

9 indexed Recurrent Adult Acute Lymphoblastic Leukemia studies · 1 recruiting (11%).

Phase mix: 0 late (III/IV) vs 9 early (I/II).

Top sponsor: National Cancer Institute (NCI) (4 trials), 5 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Adult Acute Lymphoblastic Leukemia?

PlainTrial tracks 9 US clinical trials for Recurrent Adult Acute Lymphoblastic Leukemia, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Adult Acute Lymphoblastic Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.