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2026 data Public-data reference. official source

Primary Peritoneal Cancer

Open-data reference.

28 US clinical trials · 11 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 770 participants

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Merck Sharp & Dohme

NCT06824467

RECRUITING Phase 1 612 participants

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

Regeneron Pharmaceuticals

NCT04590326

RECRUITING Phase 1 442 participants

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

Artios Pharma

NCT04657068

RECRUITING Phase 1 430 participants

Study of AVZO-021 in Patients With Advanced Solid Tumors

Avenzo Therapeutics

NCT05867251

RECRUITING NA 240 participants

REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors

Dana-Farber Cancer Institute

NCT06710548

RECRUITING Phase 3 186 participants

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

Genelux Corporation

NCT05281471

RECRUITING Phase 2 140 participants

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

AbbVie

NCT06890338

RECRUITING Phase 2 70 participants

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

University of Alabama at Birmingham

NCT04606914

RECRUITING Phase 1 60 participants

CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer

TORL Biotherapeutics

NCT07322094

RECRUITING Phase 1 50 participants

Cirtuvivint/Olaparib in Breast Cancer Susceptibility Gene/Homologous Recombination Deficiency Platinum Resistant Ovarian Cancer

University of Colorado, Denver

NCT06856499

RECRUITING Phase 1 30 participants

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Imunon

NCT05739981

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)

Imunon

NCT03393884

ACTIVE NOT RECRUITING Phase 2 125 participants

Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer

AbbVie

NCT05456685

ACTIVE NOT RECRUITING Phase 2 35 participants

Bevacizumab in Ovarian Cancer Patients With Disease at Second-Look Surgery

M.D. Anderson Cancer Center

NCT02884648

ACTIVE NOT RECRUITING Phase 2 23 participants

Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) and Imiquimod

Beth Israel Deaconess Medical Center

NCT00799110

ACTIVE NOT RECRUITING Early Phase 1 14 participants

TAME: A Pilot Study of Weekly Paclitaxel, Bevacizumab, and Tumor Associated Macrophage Targeted Therapy (Zoledronic Acid) in Women With Recurrent, Platinum-resistant, Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

M.D. Anderson Cancer Center

NCT05053750

COMPLETED Phase 2 297 participants

VTX-2337 and Pegylated Liposomal Doxorubicin (PLD) in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Celgene

NCT01666444

COMPLETED Phase 2 124 participants

Phase II ABT-888 With Cyclophosphamide

National Cancer Institute (NCI)

NCT01306032

COMPLETED Phase 2 78 participants

Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab

Yale University

NCT03093155

COMPLETED Phase 2 63 participants

CRLX101 in Combination With Bevacizumab for Recurrent Ovarian/Tubal/Peritoneal Cancer

Massachusetts General Hospital

NCT01652079

COMPLETED Phase 2 60 participants

Avastin +/- Erlotinib Consolidation Chemotherapy After Carboplatin, Paclitaxel, and Avastin (CTA) Induction Therapy for Advanced Ovarian, Fallopian Tube, Primary Peritoneal Cancer & Papillary Serous or Clear Cell Mullerian Tumors

Dana-Farber Cancer Institute

NCT00520013

COMPLETED Phase 2 32 participants

Neoadjuvant Therapy for Ovarian Cancer

Jason D. Wright

NCT01146795

COMPLETED Phase 1 27 participants

A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer

Memorial Sloan Kettering Cancer Center

NCT03245892

COMPLETED Phase 1 18 participants

Study of Safety & Biological Activity of IP IMNN-001 (also Known As GEN-1) with Neoadjuvant Chemo in Ovarian Cancer

Imunon

NCT02480374

COMPLETED Phase 1 17 participants

Dose-Escalation Study of Intraperitoneal (IP) Cisplatin, IV/IP Paclitaxel, IV Bevacizumab, and Oral Olaparib for Newly Diagnosed Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Memorial Sloan Kettering Cancer Center

NCT02121990

COMPLETED Phase 2 13 participants

Allogeneic Natural Killer (NK) Cells for Ovarian, Fallopian Tube, Peritoneal and Metastatic Breast Cancer

Masonic Cancer Center, University of Minnesota

NCT01105650

COMPLETED Phase 2 12 participants

Single Arm Study of BSI-201 in Patients With BRCA-1 or BRCA-2 Associated Advanced Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Sanofi

NCT00677079

COMPLETED Phase 1 9 participants

Neoadjuvant Chemotherapy IV Carboplatin With Weekly Paclitaxel \Bevacizumab for Primary Ovarian

Ritu Salani

NCT01219777

Phase Distribution

PhaseTrial count
Early Phase 1 12
Phase 2 13
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Primary Peritoneal Cancer Trial Landscape

ClinicalTrials.gov lists 28 US studies indexed under Primary Peritoneal Cancer, and 11 of those are currently open to recruitment — roughly 39% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Primary Peritoneal Cancer shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 25 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Primary Peritoneal Cancer is led by Imunon with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Primary Peritoneal Cancer?

PlainTrial tracks 28 US clinical trials for Primary Peritoneal Cancer, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Primary Peritoneal Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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