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NCT03393884 · ClinicalTrials.gov registry record · Phase 1

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)

A Phase 1 study of Fallopian Tube Cancer and Epithelial Ovarian Cancer, sponsored by Imunon.

Active
Registry status
Phase 1
Development phase
130
Enrollment target
20
Study locations

NCT03393884 is a Phase 1 study of Fallopian Tube Cancer and Epithelial Ovarian Cancer that is active but no longer recruiting, run by Imunon. The registered enrollment target is 130 participants, below the 254-participant average among 85 other Fallopian Tube Cancer trials with a reported enrollment target (49% lower). The trial reports 20 study locations across 13 states.

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The verdict

NCT03393884, a Phase 1 study of Fallopian Tube Cancer and Epithelial Ovarian Cancer, is active but no longer recruiting, sponsored by Imunon.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
130 participants
Enrollment target
20
Study locations

Study Summary

This is a randomized, open label, multicenter trial to evaluate the safety, dosing, efficacy and biological activity of intraperitoneal IMNN-001 plus NACT compared to NACT alone.

Interventions

  • DRUG Carboplatin
  • DRUG Paclitaxel
  • BIOLOGICAL IMNN-001

Study Locations (20)

New York

  • Monter Cancer Center - Lake Success
  • NYU Langone, Long Island - Mineola
  • NYU Langone - New York

Alabama

  • University of Alabama Birmingham - Birmingham
  • Mitchell Cancer Institute (University of South Alabama) - Mobile

California

  • Gynecologic Oncology Associates (Hoag Hospital) - Newport Beach
  • Innovative Clinical Research - Whittier

Florida

  • Advent Health - Orlando
  • Women's Care Florida - St. Petersburg

New Jersey

  • MD Anderson at Cooper - Camden
  • Hackensack University Medical Center - Hackensack

Tennessee

  • Chattanooga Women's Health - Chattanooga
  • The West Clinic - Germantown

Massachusetts

  • Massachusetts General Hospital - Boston

Missouri

  • Washington University School of Medicine in St. Louis - St Louis

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2018-09-05
Est. Completion 2026-03-30
Phase Phase 1

Sponsor

Imunon

11 total trials

What the Registry Record Tells You About NCT03393884

The ClinicalTrials.gov registry entry for NCT03393884 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 254-participant average among 85 other Fallopian Tube Cancer trials with a reported enrollment target (49% lower). The listed sponsor is Imunon, which has 11 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Fallopian Tube Cancer appearing as the primary indexed condition, and to 3 interventions - of which Carboplatin is the first listed.

NCT03393884 reports 20 study locations spanning 13 distinct geographic areas - top geographies include New York, Alabama, California.

Frequently Asked Questions

What is clinical trial NCT03393884 about?

NCT03393884 is a clinical study titled "Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)". This is a randomized, open label, multicenter trial to evaluate the safety, dosing, efficacy and biological activity of intraperitoneal IMNN-001 plus NACT compared to NACT alone.

What is the current status of trial NCT03393884?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 130 participants. The study started on 2018-09-05. Estimated completion is 2026-03-30.

What conditions does trial NCT03393884 study?

This clinical trial studies the following conditions: Fallopian Tube Cancer, Epithelial Ovarian Cancer, Primary Peritoneal Cancer.

What interventions are being tested in trial NCT03393884?

The interventions under investigation include: Carboplatin (DRUG), Paclitaxel (DRUG), IMNN-001 (BIOLOGICAL).

Who is sponsoring clinical trial NCT03393884?

This trial is sponsored by Imunon, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03393884 being conducted?

This trial has 20 study locations across Alabama, California, Florida, Massachusetts, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.