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NCT05053750 · ClinicalTrials.gov registry record · Early Phase 1
TAME: A Pilot Study of Weekly Paclitaxel, Bevacizumab, and Tumor Associated Macrophage Targeted Therapy (Zoledronic Acid) in Women With Recurrent, Platinum-resistant, Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer
A Early Phase 1 study of Primary Peritoneal Cancer and Fallopian Tube, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Early Phase 1
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT05053750 is a Early Phase 1 study of Primary Peritoneal Cancer and Fallopian Tube that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 14 participants, below the 152-participant average among 27 other Primary Peritoneal Cancer trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05053750, a Early Phase 1 study of Primary Peritoneal Cancer and Fallopian Tube, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized pilot trial of weekly paclitaxel and bevacizumab with or without zoledronic acid in women with platinum-resistant epithelial ovarian cancer with 1-2 prior regimens for recurrence.
Conditions Studied
Interventions
- DRUG Paclitaxel/Bev (control)
- DRUG Paclitaxel/Bev + ZA (experimental)
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2021-12-14 |
| Est. Completion | 2027-02-02 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05053750
The ClinicalTrials.gov registry entry for NCT05053750 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 152-participant average among 27 other Primary Peritoneal Cancer trials with a reported enrollment target (91% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Primary Peritoneal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Paclitaxel/Bev (control) is the first listed.
NCT05053750 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT05053750 about?
NCT05053750 is a clinical study titled "TAME: A Pilot Study of Weekly Paclitaxel, Bevacizumab, and Tumor Associated Macrophage Targeted Therapy (Zoledronic Acid) in Women With Recurrent, Platinum-resistant, Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer". This is a randomized pilot trial of weekly paclitaxel and bevacizumab with or without zoledronic acid in women with platinum-resistant epithelial ovarian cancer with 1-2 prior regimens for recurrence.
What is the current status of trial NCT05053750?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 14 participants. The study started on 2021-12-14. Estimated completion is 2027-02-02.
What conditions does trial NCT05053750 study?
This clinical trial studies the following conditions: Primary Peritoneal Cancer, Fallopian Tube, Epithelial Ovarian.
What interventions are being tested in trial NCT05053750?
The interventions under investigation include: Paclitaxel/Bev (control) (DRUG), Paclitaxel/Bev + ZA (experimental) (DRUG).
Who is sponsoring clinical trial NCT05053750?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05053750 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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