Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Pre-exposure Prophylaxis: full-pipeline trial registry
5 of 13 indexed Pre-exposure Prophylaxis trials are currently recruiting.
Corpus placement: #1,315 of 28,707 conditions by registered trial count.
13 US clinical trials · 5 currently recruiting · #1,315 of 28,707 conditions by registered trial count
Pre-exposure Prophylaxis: 13 US clinical trials tracked, 5 recruiting.
Pre-exposure Prophylaxis is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Public Health Foundation Enterprises, running 2 of these trials.
Enrollment posture brief
Registry condition pre-exposure-prophylaxis
OPEN 5 | RECR 38% | LATE 2 | EARLY 2 | RANK #1315 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Anaplastic Oligodendroglioma (38% recruiting · 13 trials)
Pre-exposure Prophylaxis lists 5 open slots (38% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Pre-exposure Prophylaxis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pre-exposure Prophylaxis is recruiting below its size-band peers.
5 of 13 indexed trials (38.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Pre-exposure Prophylaxis research.
Public Health Foundation Enterprises accounts for 2 of 13 trials (15.4%). 12 distinct sponsors appear on at least one study for this condition label.
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Typical Pre-exposure Prophylaxis enrolment sits around 158 participants.
Median target enrolment is 158 among the 13 trials that report a genuine target (sentinel values excluded). 4 of those (30.8%) plan for fewer than 100 participants.
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Pre-exposure Prophylaxis research is mostly interventional.
12 interventional and 1 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
13 total, page 1 of 1
Gathering Online for Dialogue and Discussion to Enhance Social Support
RTI International
NCT05753683
Hybrid Evaluation of a Home-based HIV Pre-exposure Prophylaxis Program
University of Washington
NCT05856942
Case Management Dyad
University of Chicago
NCT06162897
Stick2PrEP Cisgender Women and Trans Individuals
Columbia University
NCT05165745
Predictors of Health Service Utilizations Among Key Population in Washington DC
Us Helping Us, People Into Living
NCT06046079
Centering Those Engaged in Transactional Sex: A PrEP Innovation for Getting To Zero
University of Illinois at Chicago
NCT05929521
Information Seeking About Pre-exposure Prophylaxis
Penn State University
NCT05728034
PrEPTECH Phase 2 Study of a PrEP Telehealth Intervention
ETR Associates
NCT04902820
The Stay Study: A Demonstration Project Advancing PrEP Delivery in the San Francisco Bay Area Transgender Community
Public Health Foundation Enterprises
NCT03120936
Linking High-Risk Jail Detainees to HIV Pre-Exposure Prophylaxis: PrEP-LINK
University of Arkansas
NCT04064567
Optimizing PrEP Adherence for Young Men Who Have Sex With Men
Fenway Community Health
NCT03493555
DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence
Public Health Foundation Enterprises
NCT03387462
Assessment of a New "Boosting" Strategy for HIV Pre-exposure Prophylaxis in Healthy Volunteers
Indiana University
NCT03202511
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Pre-exposure Prophylaxis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Pre-exposure Prophylaxis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Pre-exposure Prophylaxis page
13 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Pre-exposure Prophylaxis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Public Health Foundation Enterprises sponsors the most Pre-exposure Prophylaxis trials on record, review their full trial history before evaluating a specific study. See Public Health Foundation Enterprises's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pre-exposure Prophylaxis condition card totals 13 registered trials; most-linked intervention Emtricitabine / Tenofovir Disoproxil Oral Tablet; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.