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NCT05753683 · ClinicalTrials.gov registry record · NA

Gathering Online for Dialogue and Discussion to Enhance Social Support

A NA study of HIV and Pre-exposure Prophylaxis, sponsored by RTI International.

Recruiting
Registry status
NA
Development phase
500
Enrollment target
1
Study location

NCT05753683: Recruiting NA study of HIV and Pre-exposure Prophylaxis, sponsored by RTI International.

NCT05753683 is a NA study of HIV and Pre-exposure Prophylaxis that is actively recruiting participants, run by RTI International. The registered enrollment target is 500 participants, above the 438-participant average among 303 other HIV trials with a reported enrollment target (14% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05753683, a NA study of HIV and Pre-exposure Prophylaxis, is actively recruiting participants, sponsored by RTI International.

RECRUITING
Registry status
NA
Development phase
500 participants
Enrollment target
1
Study location

Study Summary

The goal of this trial is to test a modified mobile health intervention (with a group component) relative to a mobile health intervention in a two-arm randomized trial with 500 young African American women who are human immunodeficiency virus (HIV)-negative and who misuse alcohol. The expected outcomes are to: (1) determine the efficacy of the virtual group component in reducing alcohol use and sexual risk and increasing pre-exposure prophylaxis (PrEP) utilization; and (2) understand selected outcomes for implementation. Participants will be randomized to receive either the mHealth app or the mHealth app plus the group component, and followed up at 3- and 6-months post-enrollment.

Primary Outcome

Recent alcohol (last 10 days) use will be measured by the presence of ethyl glucuronide (EtG), a breakdown product of ethanol, using an ethyl glucuronide (EtG) urine test. The One Step Ethyl Glucuronide (EtG) Test Dip Card is a lateral flow chromatographic immunoassay. Each test has a control line region to serve as a procedural control and a test line region; results with only a line in the control region and without a line in the test region are classified as positive. Urine EtG ≥300 ng/mL ind

Interventions

  • BEHAVIORAL mHealth-Women's CoOp
  • BEHAVIORAL Virtual Group

Study Locations (1)

North Carolina

  • RTI International - Durham

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2025-04-07
Est. Completion 2027-04
Phase NA
RTI International

45 total trials

What NCT05753683 shows while recruiting

NCT05753683 is an interventional study that assigns participants to a tested intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap, above the 438-participant average among 303 other HIV trials with a reported enrollment target (14% higher).

The record links to 4 conditions, with HIV appearing as the primary indexed condition, and to 2 interventions - of which mHealth-Women's CoOp is the first listed.

NCT05753683 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT05753683 about?

NCT05753683 is a clinical study titled "Gathering Online for Dialogue and Discussion to Enhance Social Support". The goal of this trial is to test a modified mobile health intervention (with a group component) relative to a mobile health intervention in a two-arm randomized trial with 500 young African American women who are human immunodeficiency virus (HIV)-negative and who misuse alcohol. The expected outc...

What is the current status of trial NCT05753683?

This trial is currently recruiting. It is a NA study. The enrollment target is 500 participants. The study started on 2025-04-07. Estimated completion is 2027-04.

What conditions does trial NCT05753683 study?

This clinical trial studies the following conditions: HIV, Pre-exposure Prophylaxis, Sexually Transmitted Infections, Alcohol Misuse.

What interventions are being tested in trial NCT05753683?

The interventions under investigation include: mHealth-Women's CoOp (BEHAVIORAL), Virtual Group (BEHAVIORAL).

Who is sponsoring clinical trial NCT05753683?

This trial is sponsored by RTI International, which has 45 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05753683 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05753683's enrollment target sits among peer trials

500 35th of 303 higher than 269 of 303 other HIV trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05753683, the US trial registry maintained by the National Library of Medicine. NCT05753683 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.